NOAEL Data REACH Registered Cosmetic Ingredient

Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1)

CAS 34644-00-3

Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) (CAS 34644-00-3) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for PANTETHEINE SULFONATE →

SOURCE NOAEL studies
NOAEL studies
4
SOURCE Chemical inventory jurisdictions
Regulatory lists
0
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1)
CAS Number
34644-00-3
DTXSID
DTXSID70956141
Molecular Formula
2C11H22N2O7S2.Ca
InChI Key
CILGDYPFLJJNKT-NAWJVIAPSA-L
Monoisotopic Mass
756.136278

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Softener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
9TK73A4X7EUNIIFDA UNII substance identifier--openFDA substances
9TK73A4X7EUNIIFDA UNII substance identifier--openFDA substances
9TK73A4X7EUNIIFDA UNII substance identifier--openFDA substances
9TK73A4X7EUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records
StatusNameEC NumberLink
RegisteredThiosulfuric acid(H2S2O3),S-[2-[[3-[[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]amino]-1-oxopropyl]amino]ethyl]ester, calcium salt (2:1)446-480-9ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1)?

Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) has 4 NOAEL studies in the database. The lowest reported value is 9TK73A4X7E UNII. Source: openFDA substances.

Is Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) used in cosmetics?

Yes, Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) is also indexed as a cosmetic ingredient under the name PANTETHEINE SULFONATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) have different safety status in cosmetics vs industrial chemicals?

Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.

Is Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) used outside industrial chemicals?

Calcium 2,4-dihydroxy-3,3-dimethyl-N-(2-{[2-(sulfosulfanyl)ethyl]carboximidato}ethyl)butanimidate--2,4-dihydroxy-N-(3-hydroxy-3-{[2-(sulfosulfanyl)ethyl]imino}propyl)-3,3-dimethylbutanimidic acid (1/1/1) also appears in cosmetics databases.