What is the NOAEL for C.I. Fluorescent Brightener 213?
C.I. Fluorescent Brightener 213 has 5 NOAEL studies in the database. The lowest reported value is 750 mg/kg bw/day via oral in Dog. Source: ToxValDB_ECHA_IUCLID.
NOAEL Data
REACH Registered
Cosmetic Ingredient
C.I. Fluorescent Brightener 213
CAS 3426-43-5
C.I. Fluorescent Brightener 213 (CAS 3426-43-5) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, AICIS, ECHA REACH.
View cosmetic safety profile for Fluorescent Brightener 236 →
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
C.I. Fluorescent Brightener 213
CAS Number
3426-43-5
DTXSID
DTXSID90889467
Molecular Formula
C34H30N10O8S2.2Na
InChI Key
BDYOOAPDMVGPIQ-UHFFFAOYSA-L
Monoisotopic Mass
816.148489
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| >15000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| ~3300 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =750 | mg/kg bw/day | NOAEL | oral | Dog | ToxValDB_ECHA_IUCLID |
| =937.5 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Disodium 4,4'-bis[(4-anilino-6-methoxy-1,3,5-triazin-2-yl)amino]stilbene-2,2'-disulphonate | 222-326-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
Is C.I. Fluorescent Brightener 213 used in cosmetics?
Yes, C.I. Fluorescent Brightener 213 is also indexed as a cosmetic ingredient under the name Fluorescent Brightener 236. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I. Fluorescent Brightener 213 come from?
Safety data is sourced from EPA ToxValDB, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is C.I. Fluorescent Brightener 213 used outside industrial chemicals?
C.I. Fluorescent Brightener 213 also appears in cosmetics databases.