NOAEL Data REACH Registered Cosmetic Ingredient

1-Octen-3-ol

Also known as: Amylvinylcarbinol, BRN 1744110, EINECS 222-226-0, FEMA No. 2805, Matsuica alcohol (+7 more)

CAS 3391-86-4

1-Octen-3-ol (CAS 3391-86-4) is a chemical substance. Key regulatory status: REACH registered, 28 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Amylvinyl Carbinol →

SOURCE noael studies public
NOAEL studies
10
SOURCE chemical inventory jurisdictions
Regulatory lists
28
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields
Name
1-Octen-3-ol
CAS Number
3391-86-4
DTXSID
DTXSID3035214
Molecular Formula
C8H16O
InChI Key
VSMOENVRRABVKN-UHFFFAOYSA-N
Monoisotopic Mass
128.120115
Synonyms
AmylvinylcarbinolBRN 1744110EINECS 222-226-0FEMA No. 2805Matsuica alcoholPentyl vinyl carbinolEPA Pesticide Chemical Code 0690371-Okten-3-olUNII-WXB511GE38mushroom alcoholoctene-1-ol-3vinyl hexanol

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 8 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 28 records
ListKeywordSource
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesCalifornia Department of Pesticide RegulationState of California
inert_ingredient; non_food_use; PesticidesEPACPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
air; detected; emissions; Europe; Other direct contact consumer goodsDanish Environmental Protection AgencyDanish EPA
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
EuropeEuropean CommissionFl@vis
active_ingredient; Europe; PesticidesCommission of the European CommunitiesCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 10 of 10 studies
ValueUnitEndpointRouteSpeciesSource
WXB511GE38UNIIFDA UNII substance identifier--openFDA substances
WXB511GE38UNIIFDA UNII substance identifier--openFDA substances
WXB511GE38UNIIFDA UNII substance identifier--openFDA substances
WXB511GE38UNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
6480ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
=340mg/kg bwLD50oralRatNTP_ICE_acute_oral
-unitlessModel Score--NTP_ICE_endocrine
14.55mg/kg bw/dayNOAELoralratCOSMOS_DB
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 10 of 10 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredOct-1-ene-3-ol222-226-0ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3183573
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for 1-Octen-3-ol?

1-Octen-3-ol has 10 NOAEL studies in the database. The lowest reported value is WXB511GE38 UNII. Source: openFDA substances.

What regulatory lists include 1-Octen-3-ol?

1-Octen-3-ol appears on 7 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, air; detected; emissions; Europe; Other direct contact consumer goods, and 4 more. Source: EPA CPDat.

Is 1-Octen-3-ol used in cosmetics?

Yes, 1-Octen-3-ol is also indexed as a cosmetic ingredient under the name Amylvinyl Carbinol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 1-Octen-3-ol come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is 1-Octen-3-ol used outside industrial chemicals?

1-Octen-3-ol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.