Danger GHS05GHS09 NOAEL Data REACH Registered Cosmetic Ingredient

Soneclosan

Also known as: Snoclosan, UNII-814H7B74XK

CAS 3380-30-1

Soneclosan (CAS 3380-30-1) is a chemical substance with GHS signal word Danger; key hazard signal: H318; H400; H410. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Hydroxydichlorodiphenyl Ether (Diclosan) →

SOURCE noael studies public
NOAEL studies
11
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields
Name
Soneclosan
CAS Number
3380-30-1
DTXSID
DTXSID80187464
Molecular Formula
C12H8Cl2O2
InChI Key
BYNQFCJOHGOKSS-UHFFFAOYSA-N
Monoisotopic Mass
253.990135
Synonyms
SnoclosanUNII-814H7B74XK

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1H318; H400; H410GHS05; GHS09Danger

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Biocide

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
active_ingredient; Europe; PesticidesCommission of the European CommunitiesCPCat
active_ingredient; Europe; PesticidesCommission of the European CommunitiesCPCat
pharmaceuticalUS International Trade CommissionCPCat
Canada; pharmaceuticalDrugBankDrugBank

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 11 of 11 studies
ValueUnitEndpointRouteSpeciesSource
814H7B74XKUNIIFDA UNII substance identifier--openFDA substances
814H7B74XKUNIIFDA UNII substance identifier--openFDA substances
814H7B74XKUNIIFDA UNII substance identifier--openFDA substances
814H7B74XKUNIIFDA UNII substance identifier--openFDA substances
=100mg/kg bw/dayLOAELoralRatToxValDB_ECHA_IUCLID
=750mg/kg bw/dayLOAELoralRatToxValDB_ECHA_IUCLID
=20mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
=30mg/kg bw/dayNOAELdermalRatToxValDB_ECHA_IUCLID
=150mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
=10mg/kg bw/dayNOELdermalRatToxValDB_ECHA_IUCLID
=50mg/kg bw/dayNOELoralRatToxValDB_ECHA_IUCLID

Showing 11 of 11 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered5-chloro-2-(4-chlorphenoxy)phenol (DCPP)429-290-0ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. If the assessment report about the chemical recommends secondary notification of the chemical in particular circumstances and any of the circumstances occur in relation to the introduction (importation or manufacture) of the chemical by a person, then the person introducing this chemical must tell us in writing within 28 calendar days that the circumstances have occurred. 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
0.3%
Category
Preservative
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL SONECLOSAN
ChEMBL Phase
2
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for Soneclosan?

Soneclosan (CAS 3380-30-1) is classified under EU CLP Annex VI as Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H318; H400; H410. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Soneclosan?

Soneclosan has 11 NOAEL studies in the database. The lowest reported value is 814H7B74XK UNII. Source: openFDA substances.

What regulatory lists include Soneclosan?

Soneclosan appears on 3 regulatory/inventory lists including active_ingredient; Europe; Pesticides, pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.

Is Soneclosan used in cosmetics?

Yes, Soneclosan is also indexed as a cosmetic ingredient under the name Hydroxydichlorodiphenyl Ether (Diclosan). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Soneclosan come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Does Soneclosan have different safety status in cosmetics vs industrial chemicals?

Soneclosan is classified GHS Danger (H318, H400, H410) in the chemicals database but is restricted in EU cosmetics at max 0.3%.

Is Soneclosan used outside industrial chemicals?

Soneclosan also appears in cosmetics, pharmaceutical databases.