What is the NOAEL for Bisdemethoxycurcumin?
Bisdemethoxycurcumin has 6 NOAEL studies in the database. The lowest reported value is 112 uL/min/10^6 cells in Human. Source: NTP_ICE_adme_parameters.
NOAEL Data
Cosmetic Ingredient
Bisdemethoxycurcumin
Also known as: 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-, 1,6-Heptadiene-3,5-dione, 1,7-bis(p-hydroxyphenyl)-, (E,E)-, (1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione, Bisdesmethoxycurcumin, Curcumin III (+4 more)
CAS 33171-05-0
Bisdemethoxycurcumin (CAS 33171-05-0) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Bisdemethoxycurcumin
CAS Number
33171-05-0
DTXSID
DTXSID00872663
Molecular Formula
C19H16O4
InChI Key
PREBVFJICNPEKM-YDWXAUTNSA-N
Monoisotopic Mass
308.104859
Synonyms
1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-1,6-Heptadiene-3,5-dione, 1,7-bis(p-hydroxyphenyl)-, (E,E)-(1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dioneBisdesmethoxycurcuminCurcumin IIIDidemethoxycurcumin1,7-Bis(4-hydroxyphenyl)-1,6-Heptadiene-3,5-dioneBis(4-hydroxycinnamoyl)methaneBis(p-hydroxycinnamoyl)methane
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Antioxidant
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 112 | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| 2EFO1BP34R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2EFO1BP34R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2EFO1BP34R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2EFO1BP34R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3.08e-8 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
Showing 6 of 6 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
BISDEMETHOXYCURCUMIN
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
5
Frequently Asked Questions
Is Bisdemethoxycurcumin used in cosmetics?
Yes, Bisdemethoxycurcumin is also indexed as a cosmetic ingredient under the name Bis-Demethoxycurcumin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Bisdemethoxycurcumin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Bisdemethoxycurcumin used outside industrial chemicals?
Bisdemethoxycurcumin also appears in cosmetics, pharmaceutical databases.