What is the NOAEL for Aminophylline?
Aminophylline has 4 NOAEL studies in the database. The lowest reported value is 27Y3KJK423 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Aminophylline
Also known as: 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1), Theophylline, compd. with ethylenediamine (2:1), Ethylenediamine, compd. with theophylline (1:2), 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1)
CAS 317-34-0
Aminophylline (CAS 317-34-0) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Aminophylline
CAS Number
317-34-0
DTXSID
DTXSID40883359
Molecular Formula
2C7H8N4O2.C2H8N2
InChI Key
FQPFAHBPWDRTLU-UHFFFAOYSA-N
Monoisotopic Mass
420.198199
Synonyms
1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1)Theophylline, compd. with ethylenediamine (2:1)Ethylenediamine, compd. with theophylline (1:2)1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1)
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Surfactant (surface active agent)Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 27Y3KJK423 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 27Y3KJK423 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 27Y3KJK423 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 27Y3KJK423 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
AMINOPHYLLINE
ChEMBL Phase
4
Adverse Events
83
Bioactivity
5
Frequently Asked Questions
What regulatory lists include Aminophylline?
Aminophylline appears on 3 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is Aminophylline used in cosmetics?
Yes, Aminophylline is also indexed as a cosmetic ingredient under the name Aminophylline. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Aminophylline come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Aminophylline used outside industrial chemicals?
Aminophylline also appears in cosmetics, pharmaceutical databases.