What is the NOAEL for Diammonium citrate?
Diammonium citrate has 4 NOAEL studies in the database. The lowest reported value is N9BUG430K8 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Diammonium citrate
Also known as: Ammonium monohydrogen citrate, Citric acid, diammonium salt, Diammonium 2-hydroxy-1,2,3-propanetricarboxylate, Dibasic ammonium citrate, EINECS 221-146-3 (+3 more)
CAS 3012-65-5
Diammonium citrate (CAS 3012-65-5) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Diammonium citrate
CAS Number
3012-65-5
DTXSID
DTXSID5020079
Molecular Formula
C6H8O7.2H3N
InChI Key
YXVFQADLFFNVDS-UHFFFAOYSA-N
Monoisotopic Mass
226.080101
Synonyms
Ammonium monohydrogen citrateCitric acid, diammonium saltDiammonium 2-hydroxy-1,2,3-propanetricarboxylateDibasic ammonium citrateEINECS 221-146-3MicrostopAmmonium citrate (2:1)UNII-N9BUG430K8
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Chelating agentpH regulating agentLubricating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| N9BUG430K8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N9BUG430K8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N9BUG430K8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N9BUG430K8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Diammonium hydrogen 2-hydroxypropane-1,2,3-tricarboxylate | 221-146-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3189066
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Diammonium citrate?
Diammonium citrate appears on 3 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Diammonium citrate used in cosmetics?
Yes, Diammonium citrate is also indexed as a cosmetic ingredient under the name Diammonium Citrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Diammonium citrate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Diammonium citrate used outside industrial chemicals?
Diammonium citrate also appears in cosmetics, pharmaceutical databases.