Danger GHS07GHS05 NOAEL Data REACH Registered Cosmetic Ingredient

(2S)-Chloropropanoic acid

CAS 29617-66-1

(2S)-Chloropropanoic acid (CAS 29617-66-1) is a chemical substance with GHS signal word Danger; key hazard signal: H312; H302; H314. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, AICIS, ECHA REACH.

View cosmetic safety profile for PVP/VA/Vinyl Propionate Copolymer →

Cross-Vertical Regulatory Divergence

(2S)-Chloropropanoic acid is classified GHS Danger (H312, H302, H314) in the chemicals database but is allowed in EU cosmetics.

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields

Name

(2S)-Chloropropanoic acid

CAS Number

29617-66-1

DTXSID

DTXSID50896915

Molecular Formula

C3H5ClO2

InChI Key

GAWAYYRQGQZKCR-REOHCLBHSA-N

Monoisotopic Mass

107.997807

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Acute Tox. 4 ; Acute Tox. 4 ; Skin Corr. 1A	H312; H302; H314	GHS07; GHS05	Danger

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies

Value	Unit	Endpoint	Route	Species	Source
PCC7J322CM	UNII	FDA UNII substance identifier	-	-	openFDA substances
PCC7J322CM	UNII	FDA UNII substance identifier	-	-	openFDA substances
PCC7J322CM	UNII	FDA UNII substance identifier	-	-	openFDA substances
PCC7J322CM	UNII	FDA UNII substance identifier	-	-	openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	(S)-2-chloropropionic acid	411-150-5	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Frequently Asked Questions

What is the GHS hazard classification for (2S)-Chloropropanoic acid?

(2S)-Chloropropanoic acid (CAS 29617-66-1) is classified under EU CLP Annex VI as Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1A with signal word Danger. Hazard statements: H312; H302; H314. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for (2S)-Chloropropanoic acid?

(2S)-Chloropropanoic acid has 4 NOAEL studies in the database. The lowest reported value is PCC7J322CM UNII. Source: openFDA substances.

Is (2S)-Chloropropanoic acid used in cosmetics?

Yes, (2S)-Chloropropanoic acid is also indexed as a cosmetic ingredient under the name PVP/VA/Vinyl Propionate Copolymer. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for (2S)-Chloropropanoic acid come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does (2S)-Chloropropanoic acid have different safety status in cosmetics vs industrial chemicals?

(2S)-Chloropropanoic acid is classified GHS Danger (H312, H302, H314) in the chemicals database but is allowed in EU cosmetics.

Is (2S)-Chloropropanoic acid used outside industrial chemicals?

(2S)-Chloropropanoic acid also appears in cosmetics databases.