What is the NOAEL for Triethoxyoctylsilane?
Triethoxyoctylsilane has 10 NOAEL studies in the database. The lowest reported value is 11.06 uL/min/10^6 cells in Human. Source: NTP_ICE_adme_parameters.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Triethoxyoctylsilane
Also known as: EINECS 220-941-2, UNII-LDC331P08E
CAS 2943-75-1
Triethoxyoctylsilane (CAS 2943-75-1) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Triethoxyoctylsilane
CAS Number
2943-75-1
DTXSID
DTXSID2029246
Molecular Formula
C14H32O3Si
InChI Key
MSRJTTSHWYDFIU-UHFFFAOYSA-N
Monoisotopic Mass
276.212071
Synonyms
EINECS 220-941-2UNII-LDC331P08E
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
31 records
BinderWaterproofing agentSealant (barrier)Processing aids not otherwise specifiedAdhesion/cohesion promoterChemical reaction regulatorThickening agentDispersing agentHardenerWetting agent (non-aqueous)Surface modifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 11.06 | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| =17.6 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| LDC331P08E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| LDC331P08E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| LDC331P08E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| LDC331P08E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.026 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HESS |
| =10000 | ppm | NOAEL | oral | Rat | ToxValDB_HESS |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Triethoxyoctylsilane | 220-941-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
UV Filter
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185786
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Triethoxyoctylsilane?
Triethoxyoctylsilane appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Triethoxyoctylsilane used in cosmetics?
Yes, Triethoxyoctylsilane is also indexed as a cosmetic ingredient under the name Triethoxycaprylylsilane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Triethoxyoctylsilane come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Triethoxyoctylsilane used outside industrial chemicals?
Triethoxyoctylsilane also appears in cosmetics, pharmaceutical, cannabis databases.