What is the NOAEL for Oridonin?
Oridonin has 4 NOAEL studies in the database. The lowest reported value is 0APJ98UCLQ UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Oridonin
Also known as: Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1alpha,6beta,7alpha,14R)-, (14R)-7-alpha,20-Epoxy-1-alpha,6-beta,7,14-tetrahydroxykaur-16-en-15-one
CAS 28957-04-2
Oridonin (CAS 28957-04-2) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
Oridonin is classified GHS CMR hazard (H351) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Oridonin
CAS Number
28957-04-2
DTXSID
DTXSID201021760
Molecular Formula
C20H28O6
InChI Key
SDHTXBWLVGWJFT-XKCURVIJSA-N
Monoisotopic Mass
364.188589
Synonyms
Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1alpha,6beta,7alpha,14R)-(14R)-7-alpha,20-Epoxy-1-alpha,6-beta,7,14-tetrahydroxykaur-16-en-15-one
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0APJ98UCLQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0APJ98UCLQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0APJ98UCLQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0APJ98UCLQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ORIDONIN
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
5
Frequently Asked Questions
Is Oridonin used in cosmetics?
Yes, Oridonin is also indexed as a cosmetic ingredient under the name ORIDONIN. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Oridonin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Oridonin have different safety status in cosmetics vs industrial chemicals?
Oridonin is classified GHS CMR hazard (H351) in the chemicals database but is allowed in EU cosmetics.
Is Oridonin used outside industrial chemicals?
Oridonin also appears in cosmetics, pharmaceutical databases.