NOAEL Data Cosmetic Ingredient

4-Ethyl-2-methoxyphenol

Also known as: EINECS 220-500-4, FEMA No. 2436, Homocresol, 4-Hydroxy-3-methoxy ethylbenzene, 1-Hydroxy-2-methoxy-4-ethylbenzene (+1 more)

CAS 2785-89-9

4-Ethyl-2-methoxyphenol (CAS 2785-89-9) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for 4-Ethylguaiacol →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
5
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
4-Ethyl-2-methoxyphenol
CAS Number
2785-89-9
DTXSID
DTXSID0047038
Molecular Formula
C9H12O2
InChI Key
CHWNEIVBYREQRF-UHFFFAOYSA-N
Monoisotopic Mass
152.08373
Synonyms
EINECS 220-500-4FEMA No. 2436Homocresol4-Hydroxy-3-methoxy ethylbenzene1-Hydroxy-2-methoxy-4-ethylbenzeneUNII-C9NFD83BJ5

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 5 records
ListKeywordSource
Cleaning products and household care - air freshener; EuropeDanish Environmental Protection AgencyDanish EPA
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
C9NFD83BJ5UNIIFDA UNII substance identifier--openFDA substances
C9NFD83BJ5UNIIFDA UNII substance identifier--openFDA substances
C9NFD83BJ5UNIIFDA UNII substance identifier--openFDA substances
C9NFD83BJ5UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3186900
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for 4-Ethyl-2-methoxyphenol?

4-Ethyl-2-methoxyphenol has 4 NOAEL studies in the database. The lowest reported value is C9NFD83BJ5 UNII. Source: openFDA substances.

What regulatory lists include 4-Ethyl-2-methoxyphenol?

4-Ethyl-2-methoxyphenol appears on 5 regulatory/inventory lists including Cleaning products and household care - air freshener; Europe, IFRA Transparency, Europe, and 2 more. Source: EPA CPDat.

Is 4-Ethyl-2-methoxyphenol used in cosmetics?

Yes, 4-Ethyl-2-methoxyphenol is also indexed as a cosmetic ingredient under the name 4-Ethylguaiacol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 4-Ethyl-2-methoxyphenol come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is 4-Ethyl-2-methoxyphenol used outside industrial chemicals?

4-Ethyl-2-methoxyphenol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.