What is the NOAEL for Isooctadecanol?
Isooctadecanol has 6 NOAEL studies in the database. The lowest reported value is 421 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Isooctadecanol
Also known as: Isooctadecan-1-ol, Isooctadecyl alcohol, Aldo 66, Emery 3389, Emery H 3600 (+13 more)
CAS 27458-93-1
Isooctadecanol (CAS 27458-93-1) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
Isooctadecanol
CAS Number
27458-93-1
DTXSID
DTXSID4051952
Synonyms
Isooctadecan-1-olIsooctadecyl alcoholAldo 66Emery 3389Emery H 3600FOC 1800Fine Oxocol 180Isostearyl alcoholJarcol I 18EXJarcol I-18CGPrisorene 3515Prisorine 3514
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
13 records
Softener and conditionerViscosity modifierThickening agentStabilizing agentFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
| IFRA Transparency | IFRA | IFRA |
| inert_ingredient; Pesticides | EPA | CPCat |
| consumer_product | P&G | Proctor & Gamble |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =421 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| Q613OCQ44Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q613OCQ44Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q613OCQ44Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q613OCQ44Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Isooctadecan-1-ol | 248-470-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emollient
Frequently Asked Questions
What regulatory lists include Isooctadecanol?
Isooctadecanol appears on 5 regulatory/inventory lists including Europe; plastic_additive, IFRA Transparency, inert_ingredient; Pesticides, and 2 more. Source: EPA CPDat.
Is Isooctadecanol used in cosmetics?
Yes, Isooctadecanol is also indexed as a cosmetic ingredient under the name Isostearyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Isooctadecanol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Isooctadecanol used outside industrial chemicals?
Isooctadecanol also appears in cosmetics databases.