What is the NOAEL for Disodium 4,4'-bis(2-sulfostyryl)biphenyl?
Disodium 4,4'-bis(2-sulfostyryl)biphenyl has 12 NOAEL studies in the database. The lowest reported value is 0 unitless. Source: NTP ICE endocrine.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Disodium 4,4'-bis(2-sulfostyryl)biphenyl
Also known as: Benzenesulfonic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-2,1-ethenediyl)bis-, disodium salt, Benzenesulfonic acid, 2,2'-((1,1'-biphenyl)-4,4'-diyldi-2,1-ethenediyl)bis-, sodium salt (1:2), Benzenesulfonic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-2,1-ethenediyl)bis-, sodium salt (1:2), Disodium 4,4'-bis-((4-anilino-6-(N-methyl-2-hydroxyethylamino)-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulfonate, EINECS 248-421-0 (+1 more)
CAS 27344-41-8
Disodium 4,4'-bis(2-sulfostyryl)biphenyl (CAS 27344-41-8) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Disodium Distyrylbiphenyl Disulfonate →
Cross-Vertical Regulatory Divergence
Disodium 4,4'-bis(2-sulfostyryl)biphenyl is classified GHS Danger (H318, H319) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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NOAEL studies
NOAEL studies
12
SOURCE
Chemical inventory jurisdictions
Regulatory lists
2
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Disodium 4,4'-bis(2-sulfostyryl)biphenyl
CAS Number
27344-41-8
DTXSID
DTXSID6036467
Molecular Formula
C28H22O6S2.2Na
InChI Key
PMPJQLCPEQFEJW-UHFFFAOYSA-L
Monoisotopic Mass
564.065319
Synonyms
Benzenesulfonic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-2,1-ethenediyl)bis-, disodium saltBenzenesulfonic acid, 2,2'-((1,1'-biphenyl)-4,4'-diyldi-2,1-ethenediyl)bis-, sodium salt (1:2)Benzenesulfonic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-2,1-ethenediyl)bis-, sodium salt (1:2)Disodium 4,4'-bis-((4-anilino-6-(N-methyl-2-hydroxyethylamino)-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulfonateEINECS 248-421-0Tinopal CBS-X
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
BrightenerSurfactant (surface active agent)UV stabilizerViscosity modifierSoftener and conditionerSurface modifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe | Danish EPA | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 12 of 12 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 4.34752515741816 | uM | AC50 | - | - | NTP ICE endocrine |
| 89.457989599688 | uM | AC50 | - | - | NTP ICE endocrine |
| 3.5774087754145 | uM | ACC | - | - | NTP ICE endocrine |
| 88.3855639650101 | uM | ACC | - | - | NTP ICE endocrine |
| =20.5 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 81G7704MYR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 81G7704MYR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 81G7704MYR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3.66 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| - | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.00215 | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.0863 | unitless | Model Score | - | - | NTP ICE endocrine |
Showing 12 of 12 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Disodium 2,2'-([1,1'-biphenyl]-4,4'-diyldivinylene)bis(benzenesulphonate) | 248-421-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
UV Filters
Frequently Asked Questions
What regulatory lists include Disodium 4,4'-bis(2-sulfostyryl)biphenyl?
Disodium 4,4'-bis(2-sulfostyryl)biphenyl appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe. Source: EPA CPDat.
Is Disodium 4,4'-bis(2-sulfostyryl)biphenyl used in cosmetics?
Yes, Disodium 4,4'-bis(2-sulfostyryl)biphenyl is also indexed as a cosmetic ingredient under the name Disodium Distyrylbiphenyl Disulfonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Disodium 4,4'-bis(2-sulfostyryl)biphenyl come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Disodium 4,4'-bis(2-sulfostyryl)biphenyl have different safety status in cosmetics vs industrial chemicals?
Disodium 4,4'-bis(2-sulfostyryl)biphenyl is classified GHS Danger (H318, H319) in the chemicals database but is allowed in EU cosmetics.
Is Disodium 4,4'-bis(2-sulfostyryl)biphenyl used outside industrial chemicals?
Disodium 4,4'-bis(2-sulfostyryl)biphenyl also appears in cosmetics databases.