What is the NOAEL for 2-Ethylhexyl nitrate?
2-Ethylhexyl nitrate has 9 NOAEL studies in the database. The lowest reported value is 0.35 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Ethylhexyl nitrate
Also known as: Nitric acid, 2-ethylhexyl ester, EINECS 248-363-6, Ethylhexyl nitrate
CAS 27247-96-7
2-Ethylhexyl nitrate (CAS 27247-96-7) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
2-Ethylhexyl nitrate
CAS Number
27247-96-7
DTXSID
DTXSID1027928
Molecular Formula
C8H17NO3
InChI Key
NKRVGWFEFKCZAP-UHFFFAOYSA-N
Monoisotopic Mass
175.120843
Synonyms
Nitric acid, 2-ethylhexyl esterEINECS 248-363-6Ethylhexyl nitrate
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.35 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| R11MG529IT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R11MG529IT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R11MG529IT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R11MG529IT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =20 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =301.007 | mg/m3 | NOAEL | inhalation | Rat | ToxValDB_HPVIS |
| >500 | mg/kg bw/day | NOAEL | dermal | Rabbit | ToxValDB_HPVIS |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-ethylhexyl nitrate | 248-363-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL401411
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is 2-Ethylhexyl nitrate used in cosmetics?
Yes, 2-Ethylhexyl nitrate is also indexed as a cosmetic ingredient under the name Diethylhexyl Succinate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Ethylhexyl nitrate come from?
Safety data is sourced from EPA ToxValDB, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Ethylhexyl nitrate used outside industrial chemicals?
2-Ethylhexyl nitrate also appears in cosmetics, pharmaceutical databases.