Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

4-Nitrophenyl aminoethylurea

CAS 27080-42-8

4-Nitrophenyl aminoethylurea (CAS 27080-42-8) is a chemical substance with GHS signal word Warning; key hazard signal: H317; H412. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for 4-Nitrophenyl Aminoethylurea →

SOURCE noael studies public
NOAEL studies
38
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
4-Nitrophenyl aminoethylurea
CAS Number
27080-42-8
DTXSID
DTXSID80873916
Molecular Formula
C9H12N4O3
InChI Key
MCKVSHDYUAVENI-UHFFFAOYSA-N
Monoisotopic Mass
224.09094

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Skin Sens. 1; Aquatic Chronic 3H317; H412GHS07Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
Europe; Personal care; restrictedEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 38 of 38 studies
ValueUnitEndpointRouteSpeciesSource
5mg/kg bw/d---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
50mg/kg bw---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
50mg/kg bw---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
125mg/kg bw---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
1G48T8PRLVUNIIFDA UNII substance identifier--openFDA substances
1G48T8PRLVUNIIFDA UNII substance identifier--openFDA substances
1mg/kg bw/dayLOAELoralratCOSMOS_DB
=0.01mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.01mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.01mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.01mg/kg bw/dNOAELoralratSCCS_vision_codex
=5mg/kg bwNOAEL-ratSCCS_vision_codex
=5mg/kg bw/dNOAEL--SCCS_vision_codex
=5mg/kg bwNOAEL-ratSCCS_vision_codex
=5mg/kg bwNOAEL-ratSCCS_vision_codex
=5mg/kg bw/dNOAEL--SCCS_vision_codex
=5mg/kg bw/dNOAEL--SCCS_vision_codex
=5mg/kg bwNOAEL-ratSCCS_vision_codex
=5mg/kg bw/dNOAEL--SCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=125mg/kg bwNOAEL-ratSCCS_vision_codex
=125mg/kg bwNOAEL-ratSCCS_vision_codex
=125mg/kg bwNOAEL-ratSCCS_vision_codex
=125mg/kg bwNOAEL-ratSCCS_vision_codex
=0.01mg/kg bw/ddermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=5mg/kg bw/ddermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=5mg/kg bw/ddermal absorptionoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
50mg/kg bwdevelopmental toxicitydermalratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
50mg/kg bwdevelopmental toxicity-ratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
5mg/kg bwgenotoxicity-ratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
125mg/kg bwgenotoxicity-ratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
5mg/kg bwrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
5mg/kg bw/dayrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
125mg/kg bwrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
125mg/kg bwrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies

Showing 38 of 38 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered[2-[(4-nitrophenyl)amino]ethyl]urea410-700-1ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for 4-Nitrophenyl aminoethylurea?

4-Nitrophenyl aminoethylurea (CAS 27080-42-8) is classified under EU CLP Annex VI as Skin Sens. 1; Aquatic Chronic 3 with signal word Warning. Hazard statements: H317; H412. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for 4-Nitrophenyl aminoethylurea?

4-Nitrophenyl aminoethylurea has 38 NOAEL studies in the database. The lowest reported value is 0.01 mg/kg bw/d via oral in rat. Source: SCCS_vision_codex.

What regulatory lists include 4-Nitrophenyl aminoethylurea?

4-Nitrophenyl aminoethylurea appears on 1 regulatory/inventory list including Europe; Personal care; restricted. Source: EPA CPDat.

Is 4-Nitrophenyl aminoethylurea used in cosmetics?

Yes, 4-Nitrophenyl aminoethylurea is also indexed as a cosmetic ingredient under the name 4-Nitrophenyl Aminoethylurea. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 4-Nitrophenyl aminoethylurea come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 4-Nitrophenyl aminoethylurea used outside industrial chemicals?

4-Nitrophenyl aminoethylurea also appears in cosmetics databases.