What is the NOAEL for Sorbitan trioleate?
Sorbitan trioleate has 6 NOAEL studies in the database. The lowest reported value is QE6F49RPJ1 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sorbitan trioleate
Also known as: Sorbitan, tri-(9Z)-9-octadecenoate, EINECS 247-569-3, Liposorb TO, Protachem STO, Rheodol SP 030 (+4 more)
CAS 26266-58-0
Sorbitan trioleate (CAS 26266-58-0) is a chemical substance. Key regulatory status: REACH registered, 15 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
15
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Sorbitan trioleate
CAS Number
26266-58-0
DTXSID
DTXSID6027892
Synonyms
Sorbitan, tri-(9Z)-9-octadecenoateEINECS 247-569-3Liposorb TOProtachem STORheodol SP 030Sorbitani trioleasTrioleate de sorbitanTrioleato de sorbitanoUNII-QE6F49RPJ1
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
EmulsifierSurfactant (surface active agent)FragranceLubricating agentDispersing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
15 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| QE6F49RPJ1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QE6F49RPJ1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QE6F49RPJ1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QE6F49RPJ1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >39800 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =50 | mg/kg bw/day | NOAEL | injection | Rat | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Anhydro-D-glucitol trioleate | 247-569-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SORBITAN TRIOLEATE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E496 — ADI: 25 mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Sorbitan trioleate?
Sorbitan trioleate appears on 7 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, pharmaceutical, and 4 more. Source: EPA CPDat.
Is Sorbitan trioleate used in cosmetics?
Yes, Sorbitan trioleate is also indexed as a cosmetic ingredient under the name Sorbitan Trioleate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sorbitan trioleate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Sorbitan trioleate used outside industrial chemicals?
Sorbitan trioleate also appears in cosmetics, pharmaceutical, food safety databases.