What is the NOAEL for Butane, 1,1'-[methylenebis(oxy)]bis-?
Butane, 1,1'-[methylenebis(oxy)]bis- has 10 NOAEL studies in the database. The lowest reported value is 126.63 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Butane, 1,1'-[methylenebis(oxy)]bis-
Also known as: Butylal, Di-n-butoxymethane, Dibutyl formal, Di-n-butyl formal, EINECS 219-909-0 (+3 more)
CAS 2568-90-3
Butane, 1,1'-[methylenebis(oxy)]bis- (CAS 2568-90-3) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Butane, 1,1'-[methylenebis(oxy)]bis-
CAS Number
2568-90-3
DTXSID
DTXSID3062528
Molecular Formula
C9H20O2
InChI Key
QLCJOAMJPCOIDI-UHFFFAOYSA-N
Monoisotopic Mass
160.14633
Synonyms
ButylalDi-n-butoxymethaneDibutyl formalDi-n-butyl formalEINECS 219-909-0Formaldehyde dibutyl acetalNSC 241UNII-V5WWR58LDU
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
SolventEmulsifierCleaning agentFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =126.63 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| V5WWR58LDU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V5WWR58LDU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V5WWR58LDU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V5WWR58LDU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| ~13109 | mg/m3 | NOEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1,1'-[methylenebis(oxy)]dibutane | 219-909-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Solvent
Frequently Asked Questions
What regulatory lists include Butane, 1,1'-[methylenebis(oxy)]bis-?
Butane, 1,1'-[methylenebis(oxy)]bis- appears on 2 regulatory/inventory lists including IFRA Transparency, drinking_water; Europe; manufacturing; plastic_additive. Source: EPA CPDat.
Is Butane, 1,1'-[methylenebis(oxy)]bis- used in cosmetics?
Yes, Butane, 1,1'-[methylenebis(oxy)]bis- is also indexed as a cosmetic ingredient under the name Dibutoxymethane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Butane, 1,1'-[methylenebis(oxy)]bis- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Butane, 1,1'-[methylenebis(oxy)]bis- used outside industrial chemicals?
Butane, 1,1'-[methylenebis(oxy)]bis- also appears in cosmetics databases.