NOAEL Data Cosmetic Ingredient

2-Nonenal

Also known as: non-2-enal, 2-Nonen-1-al, EINECS 219-562-5, FEMA No. 3213, Heptylideneacetaldehyde (+6 more)

CAS 2463-53-8

2-Nonenal (CAS 2463-53-8) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for NON-2-ENAL →

SOURCE noael studies public
NOAEL studies
8
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 17 fields
Name
2-Nonenal
CAS Number
2463-53-8
DTXSID
DTXSID3047219
Molecular Formula
C9H16O
InChI Key
BSAIUMLZVGUGKX-UHFFFAOYSA-N
Monoisotopic Mass
140.120115
Synonyms
non-2-enal2-Nonen-1-alEINECS 219-562-5FEMA No. 3213HeptylideneacetaldehydeNSC 207463-hexyl-2-propenal3-hexyl-acrolein3-hexylacroleinalpha-Nonenyl aldehydebeta-hexylacrolein

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble
EuropeEuropean CommissionFl@vis

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies
ValueUnitEndpointRouteSpeciesSource
93C6BZW2TVUNIIFDA UNII substance identifier--openFDA substances
93C6BZW2TVUNIIFDA UNII substance identifier--openFDA substances
93C6BZW2TVUNIIFDA UNII substance identifier--openFDA substances
93C6BZW2TVUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
2700ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
=5000mg/kg bwLD50oralRatNTP_ICE_acute_oral
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 8 of 8 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for 2-Nonenal?

2-Nonenal has 8 NOAEL studies in the database. The lowest reported value is 93C6BZW2TV UNII. Source: openFDA substances.

What regulatory lists include 2-Nonenal?

2-Nonenal appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, and 1 more. Source: EPA CPDat.

Is 2-Nonenal used in cosmetics?

Yes, 2-Nonenal is also indexed as a cosmetic ingredient under the name NON-2-ENAL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-Nonenal come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is 2-Nonenal used outside industrial chemicals?

2-Nonenal also appears in cosmetics, food safety, cannabis databases.