NOAEL Data Cosmetic Ingredient

Phenoxyethyl propionate

Also known as: Ethylene glycol monophenyl ether propionate, Ethanol, 2-phenoxy-, 1-propanoate, Ethanol, 2-phenoxy-, propionate, Ethanol, 2-phenoxy-, propanoate, 3-06-00-00571 (+10 more)

CAS 23495-12-7

Phenoxyethyl propionate (CAS 23495-12-7) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Phenoxyethyl Propionate →

SOURCE noael studies public
NOAEL studies
8
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 21 fields
Name
Phenoxyethyl propionate
CAS Number
23495-12-7
DTXSID
DTXSID9047203
Molecular Formula
C11H14O3
InChI Key
FKTSMIXZGPUSJB-UHFFFAOYSA-N
Monoisotopic Mass
194.094294
Synonyms
Ethylene glycol monophenyl ether propionateEthanol, 2-phenoxy-, 1-propanoateEthanol, 2-phenoxy-, propionateEthanol, 2-phenoxy-, propanoate3-06-00-00571BRN 2214059EINECS 245-692-7Ethyleneglycol monophenyl ether propionateNSC 6707Propionic acid, 2-phenoxyethyl esterUNII-7232H4RT7Q245-692-7

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies
ValueUnitEndpointRouteSpeciesSource
7232H4RT7QUNIIFDA UNII substance identifier--openFDA substances
7232H4RT7QUNIIFDA UNII substance identifier--openFDA substances
7232H4RT7QUNIIFDA UNII substance identifier--openFDA substances
7232H4RT7QUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
6480ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
=4400mg/kg bwLD50oralRatNTP_ICE_acute_oral
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 8 of 8 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3185847
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for Phenoxyethyl propionate?

Phenoxyethyl propionate has 8 NOAEL studies in the database. The lowest reported value is 7232H4RT7Q UNII. Source: openFDA substances.

What regulatory lists include Phenoxyethyl propionate?

Phenoxyethyl propionate appears on 3 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product. Source: EPA CPDat.

Is Phenoxyethyl propionate used in cosmetics?

Yes, Phenoxyethyl propionate is also indexed as a cosmetic ingredient under the name Phenoxyethyl Propionate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Phenoxyethyl propionate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is Phenoxyethyl propionate used outside industrial chemicals?

Phenoxyethyl propionate also appears in cosmetics, pharmaceutical, food safety databases.