NOAEL Data Cosmetic Ingredient

Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester

CAS 2345-24-6

Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester (CAS 2345-24-6) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for NERYL ISOBUTYRATE →

SOURCE noael studies public
NOAEL studies
11
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester
CAS Number
2345-24-6
DTXSID
DTXSID30883828
Molecular Formula
C14H24O2
InChI Key
OGJYXQFXLSCKTP-LCYFTJDESA-N
Monoisotopic Mass
224.17763

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 11 of 11 studies
ValueUnitEndpointRouteSpeciesSource
M9941BHL2OUNIIFDA UNII substance identifier--openFDA substances
M9941BHL2OUNIIFDA UNII substance identifier--openFDA substances
M9941BHL2OUNIIFDA UNII substance identifier--openFDA substances
M9941BHL2OUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
3375ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
>5000mg/kg bwLD50oralRatNTP_ICE_acute_oral
=345mg/kg bw/dayNOAELoralRatToxValDB_EFSA
=345mg/kg bw/dayNOAELoral: feedRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
=345mg/kg bw/dayNOAELoral: feedRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 11 of 11 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester?

Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester has 11 NOAEL studies in the database. The lowest reported value is M9941BHL2O UNII. Source: openFDA substances.

What regulatory lists include Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester?

Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester used in cosmetics?

Yes, Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester is also indexed as a cosmetic ingredient under the name NERYL ISOBUTYRATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester used outside industrial chemicals?

Propanoic acid, 2-methyl-, (2Z)-3,7-dimethyl-2,6-octadien-1-yl ester also appears in cosmetics, food safety, cannabis databases.