What is the NOAEL for Nicotinamide riboside chloride?
Nicotinamide riboside chloride has 10 NOAEL studies in the database. The lowest reported value is 8XM2XT8VWI UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Nicotinamide riboside chloride
CAS 23111-00-4
Nicotinamide riboside chloride (CAS 23111-00-4) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
View cosmetic safety profile for NIACINAMIDE RIBOSIDE CHLORIDE →
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
Nicotinamide riboside chloride
CAS Number
23111-00-4
DTXSID
DTXSID001355428
Molecular Formula
C11H15ClN2O5
InChI Key
YABIFCKURFRPPO-IVOJBTPCSA-N
Monoisotopic Mass
290.0669493
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
AntioxidantHumectant
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 8XM2XT8VWI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8XM2XT8VWI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8XM2XT8VWI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8XM2XT8VWI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =300 | mg/kg bw/day | NOAEL | oral | Dog | ToxValDB_EFSA |
| =300 | mg/kg bw | NOAEL | oral: gavage | Dog | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =300 | mg/kg bw | NOAEL | oral: gavage | Dog | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =325 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =325 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =325 | mg/kg bw/day | NOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Pyridinium, 3-(aminocarbonyl)-1-β-D-ribofuranosyl-, chloride (1:1) | 807-820-5 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
26
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
FDA GRAS: FDA has no questions
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is Nicotinamide riboside chloride used in cosmetics?
Yes, Nicotinamide riboside chloride is also indexed as a cosmetic ingredient under the name NIACINAMIDE RIBOSIDE CHLORIDE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Nicotinamide riboside chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Nicotinamide riboside chloride used outside industrial chemicals?
Nicotinamide riboside chloride also appears in cosmetics, pharmaceutical, food safety, cannabis databases.