NOAEL Data REACH Registered Cosmetic Ingredient

(+/-)-Miconazole nitrate

Also known as: Nitric acid--1-{2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl}-1H-imidazole (1/1), 1H-​Imidazole, 1-​[2-​(2,​4-​dichlorophenyl)​-​2-​[(2,​4-​dichlorophenyl)​methoxy]​ethyl]​-​, nitrate (1:1), 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, mononitrate, Imidazole, 1-[2,4-dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl]-, mononitrate, [2,4-Dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazole nitrate (+15 more)

CAS 22832-87-7

(+/-)-Miconazole nitrate (CAS 22832-87-7) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for Miconazole Nitrate →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields
Name
(+/-)-Miconazole nitrate
CAS Number
22832-87-7
DTXSID
DTXSID50996767
Molecular Formula
C18H14Cl4N2O.HNO3
InChI Key
MCCACAIVAXEFAL-UHFFFAOYSA-N
Monoisotopic Mass
476.981667
Synonyms
Nitric acid--1-{2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl}-1H-imidazole (1/1)1H-​Imidazole, 1-​[2-​(2,​4-​dichlorophenyl)​-​2-​[(2,​4-​dichlorophenyl)​methoxy]​ethyl]​-​, nitrate (1:1)1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, mononitrateImidazole, 1-[2,4-dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl]-, mononitrate[2,4-Dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazole nitrateAflorixAlbistatAnderginBrentanConodermConofiteDactrine

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Biocide

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
active_ingredient; AustraliaAustralian Pesticides and Veterinary Medicines AuthorityCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
VW4H1CYW1KUNIIFDA UNII substance identifier--openFDA substances
VW4H1CYW1KUNIIFDA UNII substance identifier--openFDA substances
VW4H1CYW1KUNIIFDA UNII substance identifier--openFDA substances
VW4H1CYW1KUNIIFDA UNII substance identifier--openFDA substances
=920mg/kg bwLD50oralRatNTP_ICE_acute_oral

Showing 5 of 5 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredMiconazole nitrate245-256-6ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL MICONAZOLE NITRATE
ChEMBL Phase
4
Adverse Events
21
Bioactivity
8
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for (+/-)-Miconazole nitrate?

(+/-)-Miconazole nitrate has 5 NOAEL studies in the database. The lowest reported value is VW4H1CYW1K UNII. Source: openFDA substances.

What regulatory lists include (+/-)-Miconazole nitrate?

(+/-)-Miconazole nitrate appears on 1 regulatory/inventory list including active_ingredient; Australia. Source: EPA CPDat.

Is (+/-)-Miconazole nitrate used in cosmetics?

Yes, (+/-)-Miconazole nitrate is also indexed as a cosmetic ingredient under the name Miconazole Nitrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for (+/-)-Miconazole nitrate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is (+/-)-Miconazole nitrate used outside industrial chemicals?

(+/-)-Miconazole nitrate also appears in cosmetics, pharmaceutical databases.