2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate (CAS 2277-28-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Industrial and product-use categories associated with this substance.
SOURCEEPA CPDat6 records
Softener and conditionerEmulsifierSurfactant (surface active agent)
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCENOAEL studiesShowing 4 of 4 studies
Value
Unit
Endpoint
Route
Species
Source
MGG581HK1Y
UNII
FDA UNII substance identifier
-
-
openFDA substances
MGG581HK1Y
UNII
FDA UNII substance identifier
-
-
openFDA substances
MGG581HK1Y
UNII
FDA UNII substance identifier
-
-
openFDA substances
MGG581HK1Y
UNII
FDA UNII substance identifier
-
-
openFDA substances
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCEAICIS inventory1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the introduction volume of the chemical exceeds 1 tonne per annum b. the chemical is imported as a raw ingredient 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
What is the NOAEL for 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate?
2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate has 4 NOAEL studies in the database. The lowest reported value is MGG581HK1Y UNII. Source: openFDA substances.
Is 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate used in cosmetics?
Yes, 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate is also indexed as a cosmetic ingredient under the name Glyceryl Linoleate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate used outside industrial chemicals?
2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate also appears in cosmetics, pharmaceutical databases.