NOAEL Data Cosmetic Ingredient

2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate

CAS 2277-28-3

2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate (CAS 2277-28-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Glyceryl Linoleate →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate
CAS Number
2277-28-3
DTXSID
DTXSID201016719
Molecular Formula
C21H38O4
InChI Key
WECGLUPZRHILCT-HZJYTTRNSA-N
Monoisotopic Mass
354.27701

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
Softener and conditionerEmulsifierSurfactant (surface active agent)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
MGG581HK1YUNIIFDA UNII substance identifier--openFDA substances
MGG581HK1YUNIIFDA UNII substance identifier--openFDA substances
MGG581HK1YUNIIFDA UNII substance identifier--openFDA substances
MGG581HK1YUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the introduction volume of the chemical exceeds 1 tonne per annum b. the chemical is imported as a raw ingredient 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL458250
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate?

2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate has 4 NOAEL studies in the database. The lowest reported value is MGG581HK1Y UNII. Source: openFDA substances.

Is 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate used in cosmetics?

Yes, 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate is also indexed as a cosmetic ingredient under the name Glyceryl Linoleate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is 2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate used outside industrial chemicals?

2,3-dihydroxypropyl (9Z,12Z)-octadeca-9,12-dienoate also appears in cosmetics, pharmaceutical databases.