What is the NOAEL for N-Vinylcaprolactam?
N-Vinylcaprolactam has 6 NOAEL studies in the database. The lowest reported value is 0.17 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
N-Vinylcaprolactam
Also known as: 2H-Azepin-2-one, 1-ethenylhexahydro-, 1-Vinylhexahydro-2H-azepin-2-one, EINECS 218-787-6, 1-Ethenylhexahydro-2H-azepin-2-one, UNII-KFC10CY9UP (+1 more)
CAS 2235-00-9
N-Vinylcaprolactam (CAS 2235-00-9) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
N-Vinylcaprolactam is classified GHS Danger (H302, H312, H317, H319, H335, H372) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
N-Vinylcaprolactam
CAS Number
2235-00-9
DTXSID
DTXSID1041423
Molecular Formula
C8H13NO
InChI Key
JWYVGKFDLWWQJX-UHFFFAOYSA-N
Monoisotopic Mass
139.099714
Synonyms
2H-Azepin-2-one, 1-ethenylhexahydro-1-Vinylhexahydro-2H-azepin-2-oneEINECS 218-787-61-Ethenylhexahydro-2H-azepin-2-oneUNII-KFC10CY9UP1-Ethenylazepan-2-one
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
No specific technical function
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.17 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =4.9 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| KFC10CY9UP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KFC10CY9UP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KFC10CY9UP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KFC10CY9UP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1-vinylhexahydro-2H-azepin-2-one | 218-787-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3188330
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is N-Vinylcaprolactam used in cosmetics?
Yes, N-Vinylcaprolactam is also indexed as a cosmetic ingredient under the name N-VINYL CAPROLACTAM. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N-Vinylcaprolactam come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does N-Vinylcaprolactam have different safety status in cosmetics vs industrial chemicals?
N-Vinylcaprolactam is classified GHS Danger (H302, H312, H317, H319, H335, H372) in the chemicals database but is allowed in EU cosmetics.
Is N-Vinylcaprolactam used outside industrial chemicals?
N-Vinylcaprolactam also appears in cosmetics, pharmaceutical databases.