NOAEL Data REACH Registered Cosmetic Ingredient

Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X)

Also known as: Ethylenediaminetetrakis(methylenephosphonic acid) sodium salt, Phosphonic acid, [1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt, Phosphonic acid, [ethylenebis(nitrilodimethylene)]tetra-, sodium salt, Sodium (ethylenediamine)tetramethylenephosphonate, Sodium EDTMPA (+4 more)

CAS 22036-77-7

Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X) (CAS 22036-77-7) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for Sodium EDTMP →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields

Name

Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X)

CAS Number

22036-77-7

DTXSID

DTXSID301021870

Synonyms

Ethylenediaminetetrakis(methylenephosphonic acid) sodium saltPhosphonic acid, [1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium saltPhosphonic acid, [ethylenebis(nitrilodimethylene)]tetra-, sodium saltSodium (ethylenediamine)tetramethylenephosphonateSodium EDTMPA1,2-Bis (N, N-bisphosphonomethyl) aminoethane sodium saltPhosphonic acid, P,P',P'',P'''-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:?)Phosphonic acid, [1,2-ethanediylbis[nitrilobis methylene)] tetrakis-, sodium saltSodium edtmp

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records

Chelating agent

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 2 of 2 studies

Value	Unit	Endpoint	Route	Species	Source
=0.02	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
>3250	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral

Showing 2 of 2 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	[ethylenebis[nitrilobis(methylene)]]tetrakisphosphonic acid, sodium salt	244-742-5	ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Frequently Asked Questions

What is the NOAEL for Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X)?

Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X) has 2 NOAEL studies in the database. The lowest reported value is 0.02 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

Is Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X) used in cosmetics?

Yes, Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X) is also indexed as a cosmetic ingredient under the name Sodium EDTMP. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X) used outside industrial chemicals?

Phosphonic acid, P,P′,P′′,P′′′-[1,2-ethanediylbis[nitrilobis(methylene)]]tetrakis-, sodium salt (1:X) also appears in cosmetics databases.