NOAEL Data Cosmetic Ingredient

Methylimidazoliumpropyl p-Phenylenediamine HCl

CAS 220158-86-1

Methylimidazoliumpropyl p-Phenylenediamine HCl (CAS 220158-86-1) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, SCCS.

View cosmetic safety profile for Methylimidazoliumpropyl p-Phenylenediamine HCl →

SOURCE NOAEL studies
NOAEL studies
40
SOURCE Chemical inventory jurisdictions
Regulatory lists
0
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 2 fields
Name
Methylimidazoliumpropyl p-Phenylenediamine HCl
CAS Number
220158-86-1

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 40 of 40 studies
ValueUnitEndpointRouteSpeciesSource
200mg/kg/day-oralratRegulatory source
200mg/kg/day-oralratRegulatory source
200mg/kg/day-oralratRegulatory source
=0.0183mg/kgNOAELoralratSCCS Opinion
=0.0183mg/kgNOAELoralratSCCS Opinion
=0.0183mg/kgNOAELoralratSCCS Opinion
=0.0183mg/kgNOAELoralratSCCS Opinion
=100mg/kg/dayNOAEL--SCCS Opinion
=100mg/kg bw/dNOAEL-ratSCCS Opinion
=100mg/kg/dayNOAEL--SCCS Opinion
=100mg/kg bw/dNOAEL-ratSCCS Opinion
=100mg/kg/dayNOAEL--SCCS Opinion
=100mg/kg bw/dNOAEL-ratSCCS Opinion
=100mg/kg/dayNOAEL--SCCS Opinion
=100mg/kg bw/dNOAEL-ratSCCS Opinion
=200mg/kg/dayNOAELoralratSCCS Opinion
=200mg/kg/dayNOAELoralratSCCS Opinion
=200mg/kg/dayNOAELoralratSCCS Opinion
=200mg/kg/dayNOAELoralratSCCS Opinion
=300mg/kg bw/dNOAELoralratSCCS Opinion
=300mg/kg bw/dNOAELoralratSCCS Opinion
=300mg/kg bw/dNOAELoralratSCCS Opinion
=300mg/kg bw/dNOAELoralratSCCS Opinion
=1000mg/kg bw/dNOAELoralratSCCS Opinion
=1000mg/kgNOAEL-ratSCCS Opinion
=1000mg/kg bw/dNOAELoralratSCCS Opinion
=1000mg/kgNOAEL-ratSCCS Opinion
=1000mg/kg bw/dNOAELoralratSCCS Opinion
=1000mg/kgNOAEL-ratSCCS Opinion
=1000mg/kg bw/dNOAELoralratSCCS Opinion
=1000mg/kgNOAEL-ratSCCS Opinion
=0.0183mg/kgdevelopmental toxicityoralratRegulatory source
100mg/kg/daydevelopmental toxicity--Regulatory source
100mg/kg bw/ddevelopmental toxicity-ratRegulatory source
200mg/kg/daydevelopmental toxicityoralratRegulatory source
1000mg/kg bw/ddevelopmental toxicity-ratRegulatory source
300mg/kg bw/drepeated dose toxicityoralratRegulatory source
300mg/kg bw/dreproductive toxicityoralratRegulatory source
1000mg/kg bw/dreproductive toxicityoralratRegulatory source
1000mg/kgreproductive toxicity-ratRegulatory source

Showing 40 of 40 studies

SCCS Opinions

EU Scientific Committee opinions tied to the matched substance.

SOURCE SCCS Opinion 1 opinions
OpinionDateConclusionMax Conc.Concerns
SCCS/1609/1930-31 October 2019safe2.0%strong skin sensitiser

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
2%
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Methylimidazoliumpropyl p-Phenylenediamine HCl?

Methylimidazoliumpropyl p-Phenylenediamine HCl has 40 NOAEL studies in the database. The lowest reported value is 0.0183 mg/kg via oral in rat. Source: SCCS Opinion.

Is Methylimidazoliumpropyl p-Phenylenediamine HCl used in cosmetics?

Yes, Methylimidazoliumpropyl p-Phenylenediamine HCl is also indexed as a cosmetic ingredient under the name Methylimidazoliumpropyl p-Phenylenediamine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Methylimidazoliumpropyl p-Phenylenediamine HCl come from?

Safety data is sourced from EPA ToxValDB, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Methylimidazoliumpropyl p-Phenylenediamine HCl used outside industrial chemicals?

Methylimidazoliumpropyl p-Phenylenediamine HCl also appears in cosmetics databases.