What is the NOAEL for Palmitoyl Pentapeptide-4?
Palmitoyl Pentapeptide-4 has 4 NOAEL studies in the database. The lowest reported value is KK181SM5JG UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Palmitoyl Pentapeptide-4
CAS 214047-00-4
Palmitoyl Pentapeptide-4 (CAS 214047-00-4) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Matrixyl (Palmitoyl Pentapeptide-4) →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
Palmitoyl Pentapeptide-4
CAS Number
214047-00-4
DTXSID
DTXSID401371494
Molecular Formula
C39H75N7O10
InChI Key
WSGCRSMLXFHGRM-DEVHWETNSA-N
Monoisotopic Mass
801.557541643
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
| Personal care | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
| Substances in PCP - Canada (4/2014) | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| KK181SM5JG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KK181SM5JG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KK181SM5JG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KK181SM5JG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed_with_terms
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
0.0035%
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL451881
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Palmitoyl Pentapeptide-4?
Palmitoyl Pentapeptide-4 appears on 3 regulatory/inventory lists including Canada, Personal care, Substances in PCP - Canada (4/2014). Source: EPA CPDat.
Is Palmitoyl Pentapeptide-4 used in cosmetics?
Yes, Palmitoyl Pentapeptide-4 is also indexed as a cosmetic ingredient under the name Matrixyl (Palmitoyl Pentapeptide-4). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Palmitoyl Pentapeptide-4 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Palmitoyl Pentapeptide-4 used outside industrial chemicals?
Palmitoyl Pentapeptide-4 also appears in cosmetics, pharmaceutical databases.