Also known as: 2-Propenoic acid, 2-methyl-, 1,4-butanediyl ester, Butanediol dimethacrylate, Butylene dimethacrylate, 1,4-Butylene dimethacrylate, 1,4-Butylene glycol dimethacrylate (+6 more)
CAS 2082-81-7
Butane-1,4-diyl bis(2-methylprop-2-enoate) (CAS 2082-81-7) is a chemical substance with GHS signal word Warning; key hazard signal: H317. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for 1,4-Butanediol Dimethacrylate →
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Skin Sens. 1B | H317 | GHS07 | Warning |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =14.5 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| KX6732HE0U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KX6732HE0U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KX6732HE0U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KX6732HE0U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =10 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 8 of 8 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Tetramethylene dimethacrylate | 218-218-1 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Butane-1,4-diyl bis(2-methylprop-2-enoate) (CAS 2082-81-7) is classified under EU CLP Annex VI as Skin Sens. 1B with signal word Warning. Hazard statements: H317. Source: EU CLP Annex VI (ECHA).
Butane-1,4-diyl bis(2-methylprop-2-enoate) has 8 NOAEL studies in the database. The lowest reported value is 14.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
Butane-1,4-diyl bis(2-methylprop-2-enoate) appears on 1 regulatory/inventory list including Indirect additives food contact (10/2018). Source: EPA CPDat.
Yes, Butane-1,4-diyl bis(2-methylprop-2-enoate) is also indexed as a cosmetic ingredient under the name 1,4-Butanediol Dimethacrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Butane-1,4-diyl bis(2-methylprop-2-enoate) also appears in cosmetics, pharmaceutical databases.