Also known as: N4,N4-Diethyl-2-methyl-1,4-benzenediamine monohydrochloride, 2-Amino-5-(diethylamino)toluene monoHCl, N4,N4-Diethyl-2-methylbenzene-1,4-diamine hydrochloride, 1,4-Benzenediamine, N4,N4-diethyl-2-methyl-, hydrochloride (1:1), 1,4-Benzenediamine, N4,N4-diethyl-2-methyl-, monohydrochloride (+15 more)
CAS 2051-79-8
2-Amino-5-(diethylamino)toluene monohydrochloride (CAS 2051-79-8) is a chemical substance with GHS signal word Danger; key hazard signal: H301; H319; H317; H400; H410. Key regulatory status: cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for N,N-DIETHYLTOLUENE-2,5-DIAMINE HCL →
2-Amino-5-(diethylamino)toluene monohydrochloride is classified GHS Danger (H301, H319, H317, H400, H410) in the chemicals database but is restricted in EU cosmetics at max II/1310.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 3 *; Eye Irrit. 2; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1 | H301; H319; H317; H400; H410 | GHS06; GHS09 | Danger |
Industrial and product-use categories associated with this substance.
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1.645 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1.316 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 39MIH70E0I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 39MIH70E0I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 39MIH70E0I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 39MIH70E0I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 76 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 15520 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 1021 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 816.7 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 1 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
2-Amino-5-(diethylamino)toluene monohydrochloride (CAS 2051-79-8) is classified under EU CLP Annex VI as Acute Tox. 3 *; Eye Irrit. 2; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H301; H319; H317; H400; H410. Source: EU CLP Annex VI (ECHA).
2-Amino-5-(diethylamino)toluene monohydrochloride has 11 NOAEL studies in the database. The lowest reported value is 1.316 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
Yes, 2-Amino-5-(diethylamino)toluene monohydrochloride is also indexed as a cosmetic ingredient under the name N,N-DIETHYLTOLUENE-2,5-DIAMINE HCL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
2-Amino-5-(diethylamino)toluene monohydrochloride is classified GHS Danger (H301, H319, H317, H400, H410) in the chemicals database but is restricted in EU cosmetics at max II/1310.
2-Amino-5-(diethylamino)toluene monohydrochloride also appears in cosmetics databases.