What is the NOAEL for Dibutyl ethanedioate?
Dibutyl ethanedioate has 4 NOAEL studies in the database. The lowest reported value is S18C168OWC UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Dibutyl ethanedioate
Also known as: Dibutyl oxalate, Butyl ethanedioate, Butyl oxalate, Di-n-butyl oxalate, EINECS 218-092-8 (+2 more)
CAS 2050-60-4
Dibutyl ethanedioate (CAS 2050-60-4) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Dibutyl ethanedioate is classified GHS Danger (H302, H314, H373, H315, H317, H318, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Dibutyl ethanedioate
CAS Number
2050-60-4
DTXSID
DTXSID7041916
Molecular Formula
C10H18O4
InChI Key
JKRZOJADNVOXPM-UHFFFAOYSA-N
Monoisotopic Mass
202.120509
Synonyms
Dibutyl oxalateButyl ethanedioateButyl oxalateDi-n-butyl oxalateEINECS 218-092-8NSC 8468UNII-S18C168OWC
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
SolventPlasticizerChelating agentSoftener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| S18C168OWC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S18C168OWC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S18C168OWC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S18C168OWC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Solvent
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185643
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is Dibutyl ethanedioate used in cosmetics?
Yes, Dibutyl ethanedioate is also indexed as a cosmetic ingredient under the name Dibutyl Oxalate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dibutyl ethanedioate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Dibutyl ethanedioate have different safety status in cosmetics vs industrial chemicals?
Dibutyl ethanedioate is classified GHS Danger (H302, H314, H373, H315, H317, H318, H335) in the chemicals database but is allowed in EU cosmetics.
Is Dibutyl ethanedioate used outside industrial chemicals?
Dibutyl ethanedioate also appears in cosmetics, pharmaceutical databases.