What is the NOAEL for 2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-?
2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)- has 4 NOAEL studies in the database. The lowest reported value is XZS4VD987O UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-
Also known as: Dehydrodihydroionone, EINECS 243-847-3, FEMA No. 3447, 4-(2,6,6-Trimethyl-1,3-cyclohexadien-1-yl)-2-butanone, UNII-XZS4VD987O (+6 more)
CAS 20483-36-7
2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)- (CAS 20483-36-7) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Trimethyl-1,3-Cyclohexadienylbutan-2-one →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-
CAS Number
20483-36-7
DTXSID
DTXSID0066618
Molecular Formula
C13H20O
InChI Key
SQFRYZPEWOZAKJ-UHFFFAOYSA-N
Monoisotopic Mass
192.151415
Synonyms
DehydrodihydroiononeEINECS 243-847-3FEMA No. 34474-(2,6,6-Trimethyl-1,3-cyclohexadien-1-yl)-2-butanoneUNII-XZS4VD987O4-(2,6,6-Trimethyl cyclohexa-1,3-dienyl) butane-2-one4-(2,6,6-Trimethyl-1,3-cyclohexadien-1-yl)butan-2-one4-(2,6,6-Trimethylcyclohexa-1,3-dienyl)butan-2-one7,8-Dihydro-3,4-dehydro-b-iononeDihydrodehydro-beta-iononeFEMA 3447
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| XZS4VD987O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XZS4VD987O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XZS4VD987O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XZS4VD987O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include 2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-?
2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)- appears on 2 regulatory/inventory lists including Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is 2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)- used in cosmetics?
Yes, 2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)- is also indexed as a cosmetic ingredient under the name Trimethyl-1,3-Cyclohexadienylbutan-2-one. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)- used outside industrial chemicals?
2-Butanone, 4-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)- also appears in cosmetics, food safety databases.