NOAEL Data REACH Registered Cosmetic Ingredient

9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)-

CAS 20457-75-4

9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- (CAS 20457-75-4) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Lanolinamide DEA →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)-
CAS Number
20457-75-4
DTXSID
DTXSID40885136
Molecular Formula
C23H46N2O2
InChI Key
DWIUBTKCNCCGOO-QOYCNBSOSA-N
Monoisotopic Mass
382.355929

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Anti-static agentSoftener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
367S8AA1WXUNIIFDA UNII substance identifier--openFDA substances
367S8AA1WXUNIIFDA UNII substance identifier--openFDA substances
367S8AA1WXUNIIFDA UNII substance identifier--openFDA substances
367S8AA1WXUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered[R-(Z)]-N-[3-(dimethylamino)propyl]-12-hydroxy-9-octadecenamide243-835-8ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
0.5%
Category
Surfactant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)-?

9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- has 4 NOAEL studies in the database. The lowest reported value is 367S8AA1WX UNII. Source: openFDA substances.

Is 9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- used in cosmetics?

Yes, 9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- is also indexed as a cosmetic ingredient under the name Lanolinamide DEA. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does 9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- have different safety status in cosmetics vs industrial chemicals?

9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- is classified GHS Danger (H315, H318, H410, H314, H317) in the chemicals database but is restricted in EU cosmetics at max 0.5%.

Is 9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- used outside industrial chemicals?

9-Octadecenamide, N-[3-(dimethylamino)propyl]-12-hydroxy-, (9Z,12R)- also appears in cosmetics databases.