Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl-

Also known as: 1-Hexyl-1,3,3,3-tetramethyl-1-((trimethylsilyl)oxy)disiloxane

CAS 1873-90-1

Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl- (CAS 1873-90-1) is a chemical substance with GHS signal word Warning; key hazard signal: H332; H413. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, ECHA REACH.

View cosmetic safety profile for Hexyl Methicone →

SOURCE noael studies public
NOAEL studies
1
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields
Name
Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl-
CAS Number
1873-90-1
DTXSID
DTXSID2073279
Molecular Formula
C13H34O2Si3
InChI Key
PNJMJEXVQAFSBS-UHFFFAOYSA-N
Monoisotopic Mass
306.18666
Synonyms
1-Hexyl-1,3,3,3-tetramethyl-1-((trimethylsilyl)oxy)disiloxane

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Acute Tox. 4 *; Aquatic Chronic 4H332; H413GHS07Warning

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 1 of 1 studies
ValueUnitEndpointRouteSpeciesSource
1.12mg/LLC50Inhalation-NTP_ICE_acute_inhalation

Showing 1 of 1 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered3-hexylheptamethyltrisiloxane428-700-5ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl-?

Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl- (CAS 1873-90-1) is classified under EU CLP Annex VI as Acute Tox. 4 *; Aquatic Chronic 4 with signal word Warning. Hazard statements: H332; H413. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl-?

Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl- has 1 NOAEL study in the database. The lowest reported value is 1.12 mg/L via Inhalation. Source: NTP_ICE_acute_inhalation.

Is Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl- used in cosmetics?

Yes, Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl- is also indexed as a cosmetic ingredient under the name Hexyl Methicone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl- come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl- used outside industrial chemicals?

Trisiloxane, 3-hexyl-1,1,1,3,5,5,5-heptamethyl- also appears in cosmetics databases.