What is the NOAEL for Allyl cinnamate?
Allyl cinnamate has 8 NOAEL studies in the database. The lowest reported value is N8149Z51V9 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Allyl cinnamate
Also known as: 2-Propenoic acid, 3-phenyl-, 2-propen-1-yl ester, 2-Propenoic acid, 3-phenyl-, 2-propenyl ester, Cinnamic acid, allyl ester, Cinnamate d'allyle, Allylcinnamat (+15 more)
CAS 1866-31-5
Allyl cinnamate (CAS 1866-31-5) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Allyl cinnamate
CAS Number
1866-31-5
DTXSID
DTXSID8047509
Molecular Formula
C12H12O2
InChI Key
KCMITHMNVLRGJU-UHFFFAOYSA-N
Monoisotopic Mass
188.08373
Synonyms
2-Propenoic acid, 3-phenyl-, 2-propen-1-yl ester2-Propenoic acid, 3-phenyl-, 2-propenyl esterCinnamic acid, allyl esterCinnamate d'allyleAllylcinnamatcinamato de aliloPROP-2-ENOATE, 3-PHENYL-, 2-PROPENYLAcido 2-propenoico, 3-fenil, 2-propen-1-il esterAllyl beta-phenylacrylateAllyl 3-phenylacrylateAllyl 3-phenyl-2-propenoateEINECS 217-477-8
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| N8149Z51V9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N8149Z51V9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N8149Z51V9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N8149Z51V9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =1520 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ALLYL CINNAMATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Allyl cinnamate?
Allyl cinnamate appears on 5 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 2 more. Source: EPA CPDat.
Is Allyl cinnamate used in cosmetics?
Yes, Allyl cinnamate is also indexed as a cosmetic ingredient under the name Allyl Cinnamate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Allyl cinnamate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Allyl cinnamate used outside industrial chemicals?
Allyl cinnamate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.