What is the NOAEL for 4',6,7-Trihydroxyisoflavone?
4',6,7-Trihydroxyisoflavone has 4 NOAEL studies in the database. The lowest reported value is PLM2K574GE UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
4',6,7-Trihydroxyisoflavone
Also known as: UNII-PLM2K574GE, 6,7,4'-trihydroxyisoflavone, 6-Hydroxydaidzein
CAS 17817-31-1
4',6,7-Trihydroxyisoflavone (CAS 17817-31-1) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
4',6,7-Trihydroxyisoflavone
CAS Number
17817-31-1
DTXSID
DTXSID8022452
Molecular Formula
C15H10O5
InChI Key
GYLUFQJZYAJQDI-UHFFFAOYSA-N
Monoisotopic Mass
270.052823
Synonyms
UNII-PLM2K574GE6,7,4'-trihydroxyisoflavone6-Hydroxydaidzein
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| PLM2K574GE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| PLM2K574GE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| PLM2K574GE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| PLM2K574GE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
0.02%
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL239156
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
Is 4',6,7-Trihydroxyisoflavone used in cosmetics?
Yes, 4',6,7-Trihydroxyisoflavone is also indexed as a cosmetic ingredient under the name 8-Hydroxydaidzein. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4',6,7-Trihydroxyisoflavone come from?
Safety data is sourced from EPA ToxValDB, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 4',6,7-Trihydroxyisoflavone used outside industrial chemicals?
4',6,7-Trihydroxyisoflavone also appears in cosmetics, pharmaceutical databases.