What is the NOAEL for Dihydro-beta-ionone?
Dihydro-beta-ionone has 4 NOAEL studies in the database. The lowest reported value is 710YK6CESE UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Dihydro-beta-ionone
Also known as: 2-Butanone, 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, 4-(2,6,6-Trimethyl-1-cyclohexen-1-yl)butan-2-one, EINECS 241-318-1, FEMA No. 3626, 4-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-2-butanone (+11 more)
CAS 17283-81-7
Dihydro-beta-ionone (CAS 17283-81-7) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Trimethyl-1-Cyclohexenylbutan-2-one →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
Dihydro-beta-ionone
CAS Number
17283-81-7
DTXSID
DTXSID4047200
Molecular Formula
C13H22O
InChI Key
QJJDNZGPQDGNDX-UHFFFAOYSA-N
Monoisotopic Mass
194.167065
Synonyms
2-Butanone, 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-4-(2,6,6-Trimethyl-1-cyclohexen-1-yl)butan-2-oneEINECS 241-318-1FEMA No. 36264-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-2-butanoneUNII-710YK6CESE4-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-2-butanone, 9CI4-(2,6,6-Trimethyl-1-cyclohexenyl)-2-butanone4-(2,6,6-Trimethylcyclohex-1-en-1-yl)butan-2-one5-Megastigmen-9-one7,8-Dehydro-beta-ionone7,8-dihydro-beta-ionone
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
26 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 710YK6CESE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 710YK6CESE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 710YK6CESE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 710YK6CESE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butan-2-one | 241-318-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3188345
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Dihydro-beta-ionone?
Dihydro-beta-ionone appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Dihydro-beta-ionone used in cosmetics?
Yes, Dihydro-beta-ionone is also indexed as a cosmetic ingredient under the name Trimethyl-1-Cyclohexenylbutan-2-one. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dihydro-beta-ionone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Dihydro-beta-ionone used outside industrial chemicals?
Dihydro-beta-ionone also appears in cosmetics, pharmaceutical, food safety databases.