Danger GHS06 NOAEL Data REACH Registered Cosmetic Ingredient

Magnesium hexafluorosilicate

Also known as: Silicate(2-), hexafluoro-, magnesium (1:1)

CAS 16949-65-8

Magnesium hexafluorosilicate (CAS 16949-65-8) is a chemical substance with GHS signal word Danger; key hazard signal: H301. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Magnesium Potassium Fluorosilicate →

Cross-Vertical Regulatory Divergence

Magnesium hexafluorosilicate is classified GHS Danger (H301) in the chemicals database but is restricted in EU cosmetics at max 0.15%.

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status/eu_max; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields

Name

Magnesium hexafluorosilicate

CAS Number

16949-65-8

DTXSID

DTXSID70884950

Molecular Formula

F6Si.Mg

InChI Key

INWUJAAIUAAHJA-UHFFFAOYSA-N

Monoisotopic Mass

165.952387

Synonyms

Silicate(2-), hexafluoro-, magnesium (1:1)

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Acute Tox. 3 *	H301	GHS06	Danger

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records

Pharmaceutical

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records

List	Keyword	Source
Europe; Personal care; restricted	European Commission	CosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies

Value	Unit	Endpoint	Route	Species	Source
=2.5	mg/m3	DNEL local	inhalation	Human	ToxValDB_GESTIS_DNEL
H37V80D2JS	UNII	FDA UNII substance identifier	-	-	openFDA substances
H37V80D2JS	UNII	FDA UNII substance identifier	-	-	openFDA substances
H37V80D2JS	UNII	FDA UNII substance identifier	-	-	openFDA substances
H37V80D2JS	UNII	FDA UNII substance identifier	-	-	openFDA substances

Showing 5 of 5 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Magnesium hexafluorosilicate	241-022-2	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

0.15%

Frequently Asked Questions

What is the GHS hazard classification for Magnesium hexafluorosilicate?

Magnesium hexafluorosilicate (CAS 16949-65-8) is classified under EU CLP Annex VI as Acute Tox. 3 * with signal word Danger. Hazard statements: H301. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Magnesium hexafluorosilicate?

Magnesium hexafluorosilicate has 5 NOAEL studies in the database. The lowest reported value is 2.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Magnesium hexafluorosilicate?

Magnesium hexafluorosilicate appears on 1 regulatory/inventory list including Europe; Personal care; restricted. Source: EPA CPDat.

Is Magnesium hexafluorosilicate used in cosmetics?

Yes, Magnesium hexafluorosilicate is also indexed as a cosmetic ingredient under the name Magnesium Potassium Fluorosilicate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Magnesium hexafluorosilicate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Magnesium hexafluorosilicate have different safety status in cosmetics vs industrial chemicals?

Magnesium hexafluorosilicate is classified GHS Danger (H301) in the chemicals database but is restricted in EU cosmetics at max 0.15%.

Is Magnesium hexafluorosilicate used outside industrial chemicals?

Magnesium hexafluorosilicate also appears in cosmetics databases.