What is the GHS hazard classification for Benzyl Violet 4B?
Benzyl Violet 4B (CAS 1694-09-3) is classified under EU CLP Annex VI as Carc. 2 with signal word Warning. Hazard statements: H351. Source: EU CLP Annex VI (ECHA).
Warning
GHS08
NOAEL Data
IARC Group 2B
Prop 65
Cosmetic Ingredient
Benzyl Violet 4B
Also known as: FD & C violet No. 1, C.I. Acid Violet 49, 11386 Violet, FD and C Violet No. 1, Benzenemethanaminium, N-(4-((4-(dimethylamino)phenyl)(4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-ethyl-3-sulfo-, hydroxide, inner salt, sodium salt (+15 more)
CAS 1694-09-3
Benzyl Violet 4B (CAS 1694-09-3) is a chemical substance with GHS signal word Warning; key hazard signal: H351. Key regulatory status: California Proposition 65, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, IARC, CA Prop 65.
View cosmetic safety profile for CI 42640 (FD&C Violet No. 1) →
Cross-Vertical Regulatory Divergence
Benzyl Violet 4B is prohibited in EU cosmetics but has active industrial GHS classifications (H351).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
15
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Warning
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Benzyl Violet 4B
CAS Number
1694-09-3
DTXSID
DTXSID7021441
Molecular Formula
C39H41N3O6S2.Na
InChI Key
AXMCIYLNKNGNOT-UHFFFAOYSA-M
Synonyms
FD & C violet No. 1C.I. Acid Violet 4911386 VioletFD and C Violet No. 1Benzenemethanaminium, N-(4-((4-(dimethylamino)phenyl)(4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-ethyl-3-sulfo-, hydroxide, inner salt, sodium saltAmmonium, (4-(p-(dimethylamino)-alpha-(p-(ethyl(m-sulfobenzyl)amino)phenyl)benzylidene)-2,5-cyclohexadien-1-ylidene)ethyl(m-sulfobenzyl)-, hydroxide, inner salt, sodium salt(4-((4-(Dimethylamino)phenyl)(4-(ethyl(3-sulphonatobenzyl)amino)phenyl)methylene)cyclohexa-2,5-dien-1-ylidene)(ethyl)(3-sulphonatobenzyl)ammonium, sodium saltAtlantic Acid Violet 4BNSBenzenemethanaminium, N-[4-[[4-(dimethylamino)phenyl][4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-3-sulfo-, inner salt, sodium salt (1:1)Acid Violet 5BBenzenemethanaminium, N-[4-[[4-(dimethylamino)phenyl][4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-3-sulfo-, hydroxide, inner salt, sodium saltC.I. Acid Violet 49, sodium salt
IARC Carcinogen Classification
Carcinogenic hazard classification from IARC monograph evaluations.
SOURCE
IARC Monographs on the Identification of Carcinogenic Hazards to Humans
1 records
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 2B | Possibly carcinogenic | 1987 | 16, Sup 7 |
California Proposition 65
California OEHHA listing status and toxicity category.
SOURCE
California OEHHA Proposition 65 List
1 records
| Chemical | Toxicity Type | Cancer | Developmental | Listed |
|---|---|---|---|---|
| - | cancer | Yes | No | - |
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
SOURCE
EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Carc. 2 | H351 | GHS08 | Warning |
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| OEHHA Proposition 65 (3/2019) | STATE OF CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY | OEHHA Proposition 65 List |
| OEHHA Proposition 65 (1/2023) | California Office of Environmental Health Hazard Assessment | OEHHA Proposition 65 List |
| banned; Europe; Personal care | European Commission | CosIng |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 15 of 15 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| SQE30 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| SQE30 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| SQE30 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| SQEcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| SQEcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| SQEcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| 550X5X78WK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 550X5X78WK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 550X5X78WK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 550X5X78WK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2B | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 2B | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 2B | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 2 | unitless | IARC group | - | - | NTP_ICE_cancer |
| =500 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
Showing 15 of 15 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorants
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What is the NOAEL for Benzyl Violet 4B?
Benzyl Violet 4B has 15 NOAEL studies in the database. The lowest reported value is 30 ug/day. Source: California Proposition 65.
What regulatory lists include Benzyl Violet 4B?
Benzyl Violet 4B appears on 5 regulatory/inventory lists including OEHHA Proposition 65 (3/2019), OEHHA Proposition 65 (1/2023), banned; Europe; Personal care, and 2 more. Source: EPA CPDat.
Is Benzyl Violet 4B a carcinogen according to IARC?
Benzyl Violet 4B is classified by IARC as Group 2B — possibly carcinogenic to humans (evaluated 1987). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Is Benzyl Violet 4B on the California Proposition 65 list?
Yes, Benzyl Violet 4B is listed under California Proposition 65 for cancer. Source: California OEHHA Proposition 65.
Is Benzyl Violet 4B used in cosmetics?
Yes, Benzyl Violet 4B is also indexed as a cosmetic ingredient under the name CI 42640 (FD&C Violet No. 1). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Benzyl Violet 4B come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, California Proposition 65, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Benzyl Violet 4B have different safety status in cosmetics vs industrial chemicals?
Benzyl Violet 4B is prohibited in EU cosmetics but has active industrial GHS classifications (H351).
Is Benzyl Violet 4B used outside industrial chemicals?
Benzyl Violet 4B also appears in cosmetics, cannabis databases.