What is the NOAEL for Carbonic acid, dioctyl ester?
Carbonic acid, dioctyl ester has 9 NOAEL studies in the database. The lowest reported value is 0 % via Dermal. Source: NTP_ICE_skin_sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Carbonic acid, dioctyl ester
Also known as: Dicaprylyl carbonate, Dioctyl carbonate, UNII-609A3V1SUA, Cetiol CC, Cetiol DD (+1 more)
CAS 1680-31-5
Carbonic acid, dioctyl ester (CAS 1680-31-5) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Carbonic acid, dioctyl ester
CAS Number
1680-31-5
DTXSID
DTXSID9075115
Molecular Formula
C17H34O3
InChI Key
PKPOVTYZGGYDIJ-UHFFFAOYSA-N
Monoisotopic Mass
286.250795
Synonyms
Dicaprylyl carbonateDioctyl carbonateUNII-609A3V1SUACetiol CCCetiol DDEC 434-850-2
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
15 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| range172.498 | ug/mL | CD86, EC120 | Dermal | - | NTP_ICE_skin_sensitization |
| =293 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 4.8 | % | Depletion Cys | Dermal | - | NTP_ICE_skin_sensitization |
| - | % | Depletion Lys | Dermal | - | NTP_ICE_skin_sensitization |
| 609A3V1SUA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 609A3V1SUA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 609A3V1SUA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 609A3V1SUA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | dioctyl carbonate | 434-850-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emollient
Frequently Asked Questions
What regulatory lists include Carbonic acid, dioctyl ester?
Carbonic acid, dioctyl ester appears on 3 regulatory/inventory lists including children; Europe; Personal care, Europe; Personal care, Canada; Personal care; Substances in PCP - Canada (4/2014). Source: EPA CPDat.
Is Carbonic acid, dioctyl ester used in cosmetics?
Yes, Carbonic acid, dioctyl ester is also indexed as a cosmetic ingredient under the name Dicaprylyl Carbonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Carbonic acid, dioctyl ester come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Carbonic acid, dioctyl ester used outside industrial chemicals?
Carbonic acid, dioctyl ester also appears in cosmetics databases.