CAS 16409-46-4
Butanoic acid, 3-methyl-, 5-methyl-2-(1-methylethyl)cyclohexyl ester (CAS 16409-46-4) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| E6QE751102 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E6QE751102 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E6QE751102 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E6QE751102 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 675 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Butanoic acid, 3-methyl-, 5-methyl-2-(1-methylethyl)cyclohexyl ester has 8 NOAEL studies in the database. The lowest reported value is E6QE751102 UNII. Source: openFDA substances.
Butanoic acid, 3-methyl-, 5-methyl-2-(1-methylethyl)cyclohexyl ester appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Yes, Butanoic acid, 3-methyl-, 5-methyl-2-(1-methylethyl)cyclohexyl ester is also indexed as a cosmetic ingredient under the name Menthyl Isovalerate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Butanoic acid, 3-methyl-, 5-methyl-2-(1-methylethyl)cyclohexyl ester also appears in cosmetics databases.