NOAEL Data Cosmetic Ingredient

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-

CAS 15356-74-8

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- (CAS 15356-74-8) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Tetrahydro-dimethyl-benzofuran-2-one (Mint Lactone) →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-
CAS Number
15356-74-8
DTXSID
DTXSID00864588
Molecular Formula
C11H16O2
InChI Key
IMKHDCBNRDRUEB-UHFFFAOYSA-N
Monoisotopic Mass
180.11503

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
Flavouring and nutrientFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
EuropeEuropean CommissionFl@vis
IFRA TransparencyIFRAIFRA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
BH8469LVA9UNIIFDA UNII substance identifier--openFDA substances
BH8469LVA9UNIIFDA UNII substance identifier--openFDA substances
BH8469LVA9UNIIFDA UNII substance identifier--openFDA substances
BH8469LVA9UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL DIHYDROACTINIDIOLIDE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-?

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- has 4 NOAEL studies in the database. The lowest reported value is BH8469LVA9 UNII. Source: openFDA substances.

What regulatory lists include 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-?

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- appears on 3 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe, IFRA Transparency. Source: EPA CPDat.

Is 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- used in cosmetics?

Yes, 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- is also indexed as a cosmetic ingredient under the name Tetrahydro-dimethyl-benzofuran-2-one (Mint Lactone). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Does 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- have different safety status in cosmetics vs industrial chemicals?

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- is classified GHS Danger (H300) in the chemicals database but is allowed in EU cosmetics.

Is 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- used outside industrial chemicals?

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- also appears in cosmetics, pharmaceutical, cannabis databases.