What is the NOAEL for 2-Acrylamido-2-methyl-1-propanesulfonic acid?
2-Acrylamido-2-methyl-1-propanesulfonic acid has 9 NOAEL studies in the database. The lowest reported value is 1 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Acrylamido-2-methyl-1-propanesulfonic acid
Also known as: 1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-propenyl)amino]-, Lubrizol 2404, Lubrizol AMPS, AMPS, EINECS 239-268-0 (+3 more)
CAS 15214-89-8
2-Acrylamido-2-methyl-1-propanesulfonic acid (CAS 15214-89-8) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for 2-Acrylamido-2-Methylpropane Sulfonic Acid (AMPS) →
Cross-Vertical Regulatory Divergence
2-Acrylamido-2-methyl-1-propanesulfonic acid is classified GHS Danger (H302, H332, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
2-Acrylamido-2-methyl-1-propanesulfonic acid
CAS Number
15214-89-8
DTXSID
DTXSID5027770
Molecular Formula
C7H13NO4S
InChI Key
XHZPRMZZQOIPDS-UHFFFAOYSA-N
Monoisotopic Mass
207.056529
Synonyms
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-propenyl)amino]-Lubrizol 2404Lubrizol AMPSAMPSEINECS 239-268-0UNII-490HQE5KI5EC No.: 239-268-0239-268-0
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
No specific technical function
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 490HQE5KI5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 490HQE5KI5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 490HQE5KI5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 490HQE5KI5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1830 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =5400 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =1000 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-acrylamido-2-methylpropanesulphonic acid | 239-268-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Rheology Modifier
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1907040
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Acrylamido-2-methyl-1-propanesulfonic acid?
2-Acrylamido-2-methyl-1-propanesulfonic acid appears on 1 regulatory/inventory list including drinking_water; Europe; manufacturing; plastic_additive. Source: EPA CPDat.
Is 2-Acrylamido-2-methyl-1-propanesulfonic acid used in cosmetics?
Yes, 2-Acrylamido-2-methyl-1-propanesulfonic acid is also indexed as a cosmetic ingredient under the name 2-Acrylamido-2-Methylpropane Sulfonic Acid (AMPS). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Acrylamido-2-methyl-1-propanesulfonic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Acrylamido-2-methyl-1-propanesulfonic acid have different safety status in cosmetics vs industrial chemicals?
2-Acrylamido-2-methyl-1-propanesulfonic acid is classified GHS Danger (H302, H332, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is 2-Acrylamido-2-methyl-1-propanesulfonic acid used outside industrial chemicals?
2-Acrylamido-2-methyl-1-propanesulfonic acid also appears in cosmetics, pharmaceutical, cannabis databases.