What is the NOAEL for 1-Furfurylpyrrole?
1-Furfurylpyrrole has 8 NOAEL studies in the database. The lowest reported value is 15HF30X204 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
1-Furfurylpyrrole
Also known as: 1-Furfuryl-1H-pyrrole, 1H-Pyrrole, 1-(2-furanylmethyl)-, 5-20-05-00033, BRN 0118476, EINECS 215-876-1 (+7 more)
CAS 1438-94-4
1-Furfurylpyrrole (CAS 1438-94-4) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
1-Furfurylpyrrole
CAS Number
1438-94-4
DTXSID
DTXSID5047663
Molecular Formula
C9H9NO
InChI Key
BTBFUBUCCJKJOZ-UHFFFAOYSA-N
Monoisotopic Mass
147.068414
Synonyms
1-Furfuryl-1H-pyrrole1H-Pyrrole, 1-(2-furanylmethyl)-5-20-05-00033BRN 0118476EINECS 215-876-1FEMA No. 32841-(2-Furanylmethyl)-1H-pyrroleN-Furfuryl pyrroleN-FurfurylpyrroleN-(2-Furfuryl)pyrrole1-(2-Furfuryl)pyrroleUNII-15HF30X204
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 15HF30X204 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 15HF30X204 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 15HF30X204 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 15HF30X204 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 11.2 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =25 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =25 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =25 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3187231
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1-Furfurylpyrrole?
1-Furfurylpyrrole appears on 3 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is 1-Furfurylpyrrole used in cosmetics?
Yes, 1-Furfurylpyrrole is also indexed as a cosmetic ingredient under the name 1-Furfuryl-1H-Pyrrole. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-Furfurylpyrrole come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 1-Furfurylpyrrole used outside industrial chemicals?
1-Furfurylpyrrole also appears in cosmetics, pharmaceutical, food safety, cannabis databases.