What is the NOAEL for Hexadecylamine?
Hexadecylamine has 4 NOAEL studies in the database. The lowest reported value is O2H0Q02M4P UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Hexadecylamine
Also known as: 1-Hexadecanamine, BRN 1634065, EINECS 205-596-8, Hexyldecylamine, Cetylamin (+1 more)
CAS 143-27-1
Hexadecylamine (CAS 143-27-1) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Hexadecylamine is classified GHS Danger (H314, H318, H400, H410, H302, H304, H335, H373) in the chemicals database but is restricted in EU cosmetics at max III/61.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Hexadecylamine
CAS Number
143-27-1
DTXSID
DTXSID7025390
Molecular Formula
C16H35N
InChI Key
FJLUATLTXUNBOT-UHFFFAOYSA-N
Monoisotopic Mass
241.27695
Synonyms
1-HexadecanamineBRN 1634065EINECS 205-596-8HexyldecylamineCetylaminUNII-O2H0Q02M4P
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Anti-static agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| O2H0Q02M4P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O2H0Q02M4P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O2H0Q02M4P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O2H0Q02M4P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hexadecylamine | 205-596-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
III/61
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
HEXADECYLAMINE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
Is Hexadecylamine used in cosmetics?
Yes, Hexadecylamine is also indexed as a cosmetic ingredient under the name PALMITAMINE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hexadecylamine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Hexadecylamine have different safety status in cosmetics vs industrial chemicals?
Hexadecylamine is classified GHS Danger (H314, H318, H400, H410, H302, H304, H335, H373) in the chemicals database but is restricted in EU cosmetics at max III/61.
Is Hexadecylamine used outside industrial chemicals?
Hexadecylamine also appears in cosmetics, pharmaceutical databases.