What is the NOAEL for Zinc glycinate?
Zinc glycinate has 7 NOAEL studies in the database. The lowest reported value is 681VJX72FE UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Zinc glycinate
Also known as: EINECS 238-173-1, UNII-681VJX72FE, Zinc(II) glycinate, Zinc bisglycinate, Zinc Chelazome
CAS 14281-83-5
Zinc glycinate (CAS 14281-83-5) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Zinc glycinate is classified GHS Danger (H302, H315, H318, H400) in the chemicals database but is restricted in EU cosmetics at max III/24.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Zinc glycinate
CAS Number
14281-83-5
DTXSID
DTXSID60162193
Molecular Formula
2C2H5NO2.Zn
InChI Key
UOXSXMSTSYWNMH-UHFFFAOYSA-L
Monoisotopic Mass
213.993199
Synonyms
EINECS 238-173-1UNII-681VJX72FEZinc(II) glycinateZinc bisglycinateZinc Chelazome
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
pH regulating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 681VJX72FE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 681VJX72FE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 681VJX72FE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 681VJX72FE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =500 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =500 | mg/kg bw/day | NOAEL | oral: unspecified | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =500 | mg/kg bw/day | NOAEL | oral: unspecified | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Bis(glycinato-N,O)zinc | 238-173-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
III/24
Category
pH Adjusters
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
7
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Zinc glycinate?
Zinc glycinate appears on 3 regulatory/inventory lists including Europe; supplements, Europe; food_additive; supplements, Canada; pharmaceutical. Source: EPA CPDat.
Is Zinc glycinate used in cosmetics?
Yes, Zinc glycinate is also indexed as a cosmetic ingredient under the name ZINC GLYCINATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Zinc glycinate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Zinc glycinate have different safety status in cosmetics vs industrial chemicals?
Zinc glycinate is classified GHS Danger (H302, H315, H318, H400) in the chemicals database but is restricted in EU cosmetics at max III/24.
Is Zinc glycinate used outside industrial chemicals?
Zinc glycinate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.