What is the NOAEL for Sodium octyl sulfate?
Sodium octyl sulfate has 7 NOAEL studies in the database. The lowest reported value is 285 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium octyl sulfate
Also known as: Sulfuric acid, monooctyl ester, sodium salt (1:1), Cycloryl OS, EINECS 205-535-5, Octyl sodium sulfate, Sipex ols (+3 more)
CAS 142-31-4
Sodium octyl sulfate (CAS 142-31-4) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Sodium octyl sulfate is classified GHS Danger (H228, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Sodium octyl sulfate
CAS Number
142-31-4
DTXSID
DTXSID9036226
Molecular Formula
C8H18O4S.Na
InChI Key
WFRKJMRGXGWHBM-UHFFFAOYSA-M
Synonyms
Sulfuric acid, monooctyl ester, sodium salt (1:1)Cycloryl OSEINECS 205-535-5Octyl sodium sulfateSipex olsSodium capryl sulfateUNII-6RZL727210Sulfuric acid, monooctyl ester, sodium salt
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
Surfactant (surface active agent)Solubility enhancer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =285 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 6RZL727210 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6RZL727210 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6RZL727210 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6RZL727210 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3200 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium octyl sulphate | 205-535-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SODIUM OCTYL SULFATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Sodium octyl sulfate?
Sodium octyl sulfate appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, SCIL (9/2019). Source: EPA CPDat.
Is Sodium octyl sulfate used in cosmetics?
Yes, Sodium octyl sulfate is also indexed as a cosmetic ingredient under the name Sodium Caprylyl Sulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium octyl sulfate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Sodium octyl sulfate have different safety status in cosmetics vs industrial chemicals?
Sodium octyl sulfate is classified GHS Danger (H228, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is Sodium octyl sulfate used outside industrial chemicals?
Sodium octyl sulfate also appears in cosmetics, pharmaceutical databases.