What is the NOAEL for 1-Monolaurin?
1-Monolaurin has 6 NOAEL studies in the database. The lowest reported value is WR963Y5QYW UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1-Monolaurin
Also known as: 2,3-dihydroxypropyl dodecanoate, 1-Lauroyl-rac-glycerol, EINECS 205-526-6, Glucerol alpha-monolaurate, Glycerin 1-monolaurate (+15 more)
CAS 142-18-7
1-Monolaurin (CAS 142-18-7) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
8
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
1-Monolaurin
CAS Number
142-18-7
DTXSID
DTXSID5041275
Molecular Formula
C15H30O4
InChI Key
ARIWANIATODDMH-UHFFFAOYSA-N
Monoisotopic Mass
274.214409
Synonyms
2,3-dihydroxypropyl dodecanoate1-Lauroyl-rac-glycerolEINECS 205-526-6Glucerol alpha-monolaurateGlycerin 1-monolaurateGlycerol 1-laurateGlycerol 1-monolaurateGlyceryl laurate1-Glyceryl laurateGlyceryl monododecanoateLauric acid alpha-monoglyceridealpha-Monolaurin
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
17 records
Softener and conditionerEmulsifierSurfactant (surface active agent)Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| IFRA Transparency | IFRA | IFRA |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| WR963Y5QYW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WR963Y5QYW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WR963Y5QYW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WR963Y5QYW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =280 | mg/m3 | NOEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,3-dihydroxypropyl laurate | 205-526-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
preservative_booster
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
GLYCEROL MONOLAURATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include 1-Monolaurin?
1-Monolaurin appears on 6 regulatory/inventory lists including active_ingredient; Europe; Pesticides, IFRA Transparency, inert_ingredient; Pesticides, and 3 more. Source: EPA CPDat.
Is 1-Monolaurin used in cosmetics?
Yes, 1-Monolaurin is also indexed as a cosmetic ingredient under the name Glyceryl Laurate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-Monolaurin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is 1-Monolaurin used outside industrial chemicals?
1-Monolaurin also appears in cosmetics, pharmaceutical, food safety databases.