What is the NOAEL for Citronellyl butyrate?
Citronellyl butyrate has 10 NOAEL studies in the database. The lowest reported value is IY68QPD54V UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Citronellyl butyrate
Also known as: Butanoic acid, 3,7-dimethyl-6-octen-1-yl ester, 6-Octen-1-ol, 3,7-dimethyl-, butyrate, 2-02-00-00248, BRN 1707201, Butyric acid, 3,7-dimethyl-6-octenyl ester (+14 more)
CAS 141-16-2
Citronellyl butyrate (CAS 141-16-2) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Citronellyl butyrate
CAS Number
141-16-2
DTXSID
DTXSID5047405
Molecular Formula
C14H26O2
InChI Key
XQPZQXTWYZAXAK-UHFFFAOYSA-N
Monoisotopic Mass
226.19328
Synonyms
Butanoic acid, 3,7-dimethyl-6-octen-1-yl ester6-Octen-1-ol, 3,7-dimethyl-, butyrate2-02-00-00248BRN 1707201Butyric acid, 3,7-dimethyl-6-octenyl esterButyric acid, ester with citronellolCitronellyl butanoateCitronellyl n-butyrate2,6-Dimethyl-2-octen-8-ol, butyrate3,7-Dimethyl-6-octenyl butanoate2,6-Dimethyl-2-octen-8-yl butyrate3,7-Dimethyl-6-octen-1-yl butyrate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| IY68QPD54V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| IY68QPD54V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| IY68QPD54V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| IY68QPD54V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 3240 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_EFSA |
| =50 | mg/kg bw/day | NOEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =50 | mg/kg bw/day | NOEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Citronellyl butyrate | 205-463-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185221
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Citronellyl butyrate?
Citronellyl butyrate appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Citronellyl butyrate used in cosmetics?
Yes, Citronellyl butyrate is also indexed as a cosmetic ingredient under the name Citronellyl Butyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Citronellyl butyrate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Citronellyl butyrate used outside industrial chemicals?
Citronellyl butyrate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.