What is the NOAEL for Benzyl cyanide?
Benzyl cyanide has 8 NOAEL studies in the database. The lowest reported value is 23G40PRP93 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Benzyl cyanide
Also known as: Phenylacetonitrile, Benzeneacetonitrile, Acetic acid, phenyl-nitrile, Benzylnitrile, EINECS 205-410-5 (+6 more)
CAS 140-29-4
Benzyl cyanide (CAS 140-29-4) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Benzyl cyanide is classified GHS Danger (H301, H302, H311, H330, H319, H372) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Benzyl cyanide
CAS Number
140-29-4
DTXSID
DTXSID2021492
Molecular Formula
C8H7N
InChI Key
SUSQOBVLVYHIEX-UHFFFAOYSA-N
Monoisotopic Mass
117.057849
Synonyms
PhenylacetonitrileBenzeneacetonitrileAcetic acid, phenyl-nitrileBenzylnitrileEINECS 205-410-5Phenyl acetyl nitrileToluene, alpha-cyano-BenzylkyanidUNII-23G40PRP93alpha-cyanotoluenealpha-tolunitrile
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
DeodorizerFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| consumer_product | P&G | Proctor & Gamble |
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 23G40PRP93 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 23G40PRP93 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 23G40PRP93 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 23G40PRP93 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 0.43 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Phenylacetonitrile | 205-410-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3560735
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Benzyl cyanide?
Benzyl cyanide appears on 2 regulatory/inventory lists including consumer_product, banned; Europe; Personal care. Source: EPA CPDat.
Is Benzyl cyanide used in cosmetics?
Yes, Benzyl cyanide is also indexed as a cosmetic ingredient under the name Phenylacetonitrile. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Benzyl cyanide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Benzyl cyanide have different safety status in cosmetics vs industrial chemicals?
Benzyl cyanide is classified GHS Danger (H301, H302, H311, H330, H319, H372) in the chemicals database but is allowed in EU cosmetics.
Is Benzyl cyanide used outside industrial chemicals?
Benzyl cyanide also appears in cosmetics, pharmaceutical databases.