What is the NOAEL for 2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol?
2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol has 4 NOAEL studies in the database. The lowest reported value is K5APE098ZI UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol
Also known as: Ethanol, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, EINECS 205-396-0, Ethylenediamine tetraethanol, Ethylenediamine, N,N,N',N'-tetrakis(2-hydroxyethyl)-, 2,2',2'',2'''-(Ethylenediimino)tetraethanol (+8 more)
CAS 140-07-8
2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol (CAS 140-07-8) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Tetrahydroxyethyl Ethylenediamine →
Cross-Vertical Regulatory Divergence
2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol is classified GHS Danger (H302, H315, H318) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol
CAS Number
140-07-8
DTXSID
DTXSID2041917
Molecular Formula
C10H24N2O4
InChI Key
BYACHAOCSIPLCM-UHFFFAOYSA-N
Monoisotopic Mass
236.173607
Synonyms
Ethanol, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-EINECS 205-396-0Ethylenediamine tetraethanolEthylenediamine, N,N,N',N'-tetrakis(2-hydroxyethyl)-2,2',2'',2'''-(Ethylenediimino)tetraethanolEthylenedinitrilotetraethanolNSC 21705Tetra(hydroxyethyl)ethylenediamineN,N,N',N'-Tetrakis(2-hydroxyethyl)-1,2-diaminoethaneTetrakis(hydroxyethyl)ethylenediamineN,N,N',N'-Tetrakis(hydroxyethyl)ethylenediamineN,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Chelating agentpH regulating agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| K5APE098ZI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K5APE098ZI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K5APE098ZI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K5APE098ZI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Rheology Modifier
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3187444
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is 2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol used in cosmetics?
Yes, 2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol is also indexed as a cosmetic ingredient under the name Tetrahydroxyethyl Ethylenediamine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol have different safety status in cosmetics vs industrial chemicals?
2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol is classified GHS Danger (H302, H315, H318) in the chemicals database but is allowed in EU cosmetics.
Is 2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol used outside industrial chemicals?
2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetrakisethanol also appears in cosmetics, pharmaceutical databases.